Palatal mucormycosis in patients with hematologic malignancy and stem cell transplantation.

Abstract

We present two patients with acute myelogenous leukemia who developed palatal mucormycosis, as well as a review of 15 well described reported cases of the same condition in patients who had hematologic malignancy and had undergone hematopoietic stem cell transplantation. Early diagnosis of palatal mucormycosis requires high suspicion of the disease along with a thorough oral examination. Mucormycosis is a devastating disease with a high mortality rate, thereby stressing the importance for early appropriate antifungal therapy in immunocompromised patients with palatal lesions while awaiting the results of histopathology and cultures.

• Authors: Fadi Al Akhrass, Labib Debiane, Lina Abdallah, Leyla Best, Victor Mulanovich, Kenneth Rolston, Dimitrios P Kontoyiannis
• Journal: Medical mycology (Med Mycol) Vol. 49 Issue 4 Pg. 400-5 (May 2011) ISSN: 1460-2709 [Electronic] England
• PMID: 21077735 (Publication Type: Case Reports, Journal Article, Review)

Topics

• Adolescent
• Adult
• Aged
• Child
• Child, Preschool
• Fatal Outcome
• Female
• Hematologic Neoplasms (complications, microbiology)
• Hematopoietic Stem Cell Transplantation
• Humans
• Male
• Middle Aged
• Mucormycosis (complications, microbiology)
• Opportunistic Infections (complications)
• Palate, Hard (microbiology)
• Young Adult