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Sandostatin desensitization--a strategy useful for patients with carcinoid tumors, intolerant to sandostatin.

Abstract
Sandostatin immediate release (IR) is frequently used to treat patients with carcinoid tumors. However, some patients are unable to tolerate the immediate side effects of sandostatin IR leading to discontinuation of the drug. There is no literature available to guide the management of patients' sensitivity/intolerance to sandostatin IR. We report a 49-year-old male with carcinoid tumor who was intolerant to sandostatin IR initially but was able to tolerate the drug after we employed a desensitization strategy.
AuthorsSanjay Vinjamaram, Renuka Iyer
JournalCancer chemotherapy and pharmacology (Cancer Chemother Pharmacol) Vol. 68 Issue 1 Pg. 225-6 (Jul 2011) ISSN: 1432-0843 [Electronic] Germany
PMID20922390 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antineoplastic Agents, Hormonal
  • Octreotide
Topics
  • Antineoplastic Agents, Hormonal (administration & dosage, adverse effects, therapeutic use)
  • Carcinoid Tumor (drug therapy)
  • Desensitization, Immunologic
  • Humans
  • Male
  • Middle Aged
  • Octreotide (administration & dosage, adverse effects, therapeutic use)
  • Pancreatic Neoplasms (drug therapy)

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