Chlorine inactivation of human norovirus, murine norovirus and poliovirus in drinking water.

Abstract

AIMS:

To evaluate the reduction of human norovirus (HuNoV) by chlorine disinfection under typical drinking water treatment conditions.

METHODS AND RESULTS:

HuNoV, murine norovirus (MNV) and poliovirus type 1 (PV1) were inoculated into treated water before chlorination, collected from a drinking water treatment plant, and bench-scale free chlorine disinfection experiments were performed for two initial free chlorine concentrations, 0.1 and 0.5 mg l(-1). Inactivation of MNV reached more than 4 log(10) after 120 and 0.5 min contact time to chlorine at the initial free chlorine concentrations of 0.1 and 0.5 mg l(-1), respectively.

CONCLUSIONS:

MNV was inactivated faster than PV1, and there was no significant difference in the viral RNA reduction rate between HuNoV and MNV. The results suggest that appropriate water treatment process with chlorination can manage the risk of HuNoV infection via drinking water supply systems.

SIGNIFICANCE AND IMPACT OF THE STUDY:

The data obtained in this study would be useful for assessing or managing the risk of HuNoV infections from drinking water exposure.

• Authors: M Kitajima, Y Tohya, K Matsubara, E Haramoto, E Utagawa, H Katayama
• Journal: Letters in applied microbiology (Lett Appl Microbiol) Vol. 51 Issue 1 Pg. 119-21 (Jul 2010) ISSN: 1472-765X [Electronic] England
• PMID: 20536708 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Disinfectants
• Chlorine

Topics

• Animals
• Cell Line
• Chlorine (pharmacology)
• Disinfectants (pharmacology)
• Disinfection (methods)
• Humans
• Norovirus (drug effects)
• Poliovirus (drug effects)
• Time Factors
• Viral Load
• Viral Plaque Assay
• Virus Inactivation
• Water Microbiology
• Water Purification (methods)