Relationship between whole blood serotonin and repetitive behaviors in autism.

Abstract

This study was conducted to examine the relationship between whole blood serotonin level and behavioral symptoms in 78 subjects with autism. No significant associations were found between serotonin level and the primary behavioral outcome measures. However, a significant inverse relationship between serotonin level and self-injury was demonstrated.

• Authors: Alexander Kolevzon, Jeffrey H Newcorn, Lauren Kryzak, William Chaplin, Dryden Watner, Eric Hollander, Christopher J Smith, Edwin H Cook Jr, Jeremy M Silverman
• Journal: Psychiatry research (Psychiatry Res) Vol. 175 Issue 3 Pg. 274-6 (Feb 28 2010) ISSN: 0165-1781 [Print] Ireland
• PMID: 20044143 (Publication Type: Journal Article, Research Support, N.I.H., Extramural, Research Support, Non-U.S. Gov't, Research Support, U.S. Gov't, P.H.S.)
• Copyright: 2009 Elsevier Ltd. All rights reserved.

Chemical References

• Serotonin

Topics

• Adolescent
• Autistic Disorder (blood, complications)
• Child
• Child, Preschool
• Cumulative Trauma Disorders (blood, etiology)
• Female
• Humans
• Male
• Psychiatric Status Rating Scales
• Self-Injurious Behavior (blood, etiology)
• Serotonin (blood)