Abstract | BACKGROUND: METHODS: We prospectively followed up 61,433 women who were cancer free at baseline in 1987-1990. Coffee and tea consumption was assessed with a food-frequency questionnaire administered at baseline and in 1997. Incident invasive breast cancer cases were ascertained by linkage with Swedish Cancer registers. RESULTS: Over a mean follow-up of 17.4 years, through December 2007, there were 2,952 incident cases of invasive breast cancer identified. Coffee consumption was not associated with risk of overall breast cancer (multivariate relative risk (RR) for ≥ 4 cups/day versus <1 cup/day = 1.02; 95% CI, 0.87-1.20) or with any subtype defined by ER and PR status. Black tea consumption was significantly positively associated with risk of overall breast cancer and ER+/PR+ tumors. The multivariate RRs comparing ≥ 2 cups/day of tea with no consumption were 1.22 (95% CI, 1.05-1.42) for overall breast cancer and 1.36 (95% CI, 1.09-1.69) for ER+/PR+ tumors. CONCLUSION: Findings from this prospective study do not support a role of coffee consumption in the development of breast cancer but suggest that black tea consumption may be positively associated with risk of ER+/PR+ tumors.
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Authors | Susanna C Larsson, Leif Bergkvist, Alicja Wolk |
Journal | Cancer causes & control : CCC
(Cancer Causes Control)
Vol. 20
Issue 10
Pg. 2039-44
(Dec 2009)
ISSN: 1573-7225 [Electronic] Netherlands |
PMID | 19597749
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Coffee
- Receptors, Estrogen
- Receptors, Progesterone
- Tea
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Topics |
- Adult
- Aged
- Beverages
- Breast Neoplasms
(epidemiology, etiology, metabolism)
- Carcinoma
(epidemiology, etiology, metabolism)
- Coffee
- Cohort Studies
- Drinking Behavior
(physiology)
- Female
- Humans
- Middle Aged
- Receptors, Estrogen
(metabolism)
- Receptors, Progesterone
(metabolism)
- Risk Factors
- Sweden
(epidemiology)
- Tea
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