Abstract |
Histone modifications tend to be lost during chromosome duplication. Several recent studies suggest that the RNA interference pathway becomes active during the weakened transcriptional repression occurring at centromeres in S phase, resulting in the re-establishment of histone modifications that direct the formation of heterochromatin.
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Authors | Geneviève Thon |
Journal | Current biology : CB
(Curr Biol)
Vol. 18
Issue 9
Pg. R380-2
(May 06 2008)
ISSN: 0960-9822 [Print] England |
PMID | 18460317
(Publication Type: Journal Article, Comment)
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Chemical References |
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Topics |
- DNA Replication
(physiology)
- Heterochromatin
(metabolism)
- Histones
(metabolism)
- RNA Interference
(physiology)
- S Phase
(physiology)
- Schizosaccharomyces
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