[Drug therapy of hyperthyroidism].

Abstract

The possibilities of the treatment of hyperthyroidism are mentioned, in which cases the author especially deals with the medicamentous therapy, taking into consideration the different chemical groups (imidazol derivations, thiourazil derivations, perchlorates) and their therapeutic mechanisms. The indications and contraindications of this treatment and the possible side effects are compiled in form of a table. The in-vitro-parameters which are necessary for the observation of the course are estimated in their significance. The author deals with the problems of the additional treatment. Taking into consideration indications and contraindications as well as controls of the course of functional parameters the medicamentous therapy concerned is a treatment with a good prognosis. It is promising particularly in such cases, when suitable parameters are used for the solution of the question concerning the end of the therapy. For this purpose nowadays two tests are at our disposal: 1. modified Alexander's test (radioiodine-test and suppression test under thyreostatic therapy) and 2. TRH-test with radioimmunological determination of TSH. The treatment should be carried out in adequate endocrinological dispensaries, as there are certain risks in not optimal therapy.

• Authors: H J Heberling, J Gauer, D Lohmann
• Journal: Zeitschrift fur die gesamte innere Medizin und ihre Grenzgebiete (Z Gesamte Inn Med) Vol. 31 Issue 13 Pg. 497-500 (Jul 01 1976) ISSN: 0044-2542 [Print] Germany
• Vernacular Title: Medikaentöse Therapie der Hyperthyreose
• PMID: 183393 (Publication Type: English Abstract, Journal Article)

Chemical References

• Perchlorates
• Methimazole
• Thiouracil

Topics

• Conjunctivitis (chemically induced)
• Drug Eruptions (etiology)
• Fever (chemically induced)
• Humans
• Hyperthyroidism (drug therapy)
• Methimazole (adverse effects, therapeutic use)
• Nausea (chemically induced)
• Perchlorates (adverse effects, therapeutic use)
• Thiouracil (adverse effects, therapeutic use)