No higher risk of myocardial infarction among bipolar patients in a 6-year follow-up of acute mood episodes.

Abstract

OBJECTIVE:

The aim of this study is to estimate the risk of acute myocardial infarction (AMI) among bipolar disorder patients during a 6-year follow-up after acute mood episodes. The risk is compared with that of a cohort of patients who underwent appendectomy operations during the same period.

METHODS:

We used administrative claims data from the Taiwan National Health Insurance Research Database covering the years 1997-2002, with the two study cohorts comprising patients hospitalized for bipolar disorder (n = 1429) or appendectomies (n = 4993) in 1997. Multiple logistic regression analyses were performed to compare the crude odds ratio of patients in these cohorts developing AMI following the index discharge by gender.

RESULTS:

A total of 2.24% of the bipolar disorder patients developed AMI during the 6-year follow-up period, when compared with 1.72% of the appendectomy patients. The multiple logistic regression analyses revealed that there were no significant relationships between the patients in the two cohorts developing AMI, regardless of gender.

CONCLUSIONS:

There were no significant differences in the risk of developing AMI between patients with bipolar disorder and patients undergoing appendectomy operations, when compared either by gender or as whole groups.

• Authors: Herng-Ching Lin, Shang-Ying Tsai, Hsin-Chien Lee
• Journal: Psychosomatic medicine (Psychosom Med) Vol. 70 Issue 1 Pg. 73-6 (Jan 2008) ISSN: 1534-7796 [Electronic] United States
• PMID: 18158377 (Publication Type: Journal Article)

Topics

• Aged
• Appendectomy
• Bipolar Disorder
• Case-Control Studies
• Cohort Studies
• Female
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Myocardial Infarction (epidemiology, psychology)
• Odds Ratio
• Risk Factors