HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Successful unrelated bone marrow transplantation in a child with chronic granulomatous disease complicated by pulmonary and cerebral granuloma formation.

Abstract
We report on a 6-year-old boy with chronic granulomatous disease (CGD) complicated by chronic inflammatory reactions with formation of large pulmonary granuloma as well as intracerebral lesions. Bone marrow transplantation (BMT) from an unrelated donor led to stable reconstitution, to rapid resolution of pulmonary granuloma, and to rapid resolution of intracerebral lesions.
AuthorsCatharina Schuetz, Manfred Hoenig, Ansgar Schulz, Min Ae Lee-Kirsch, Joachim Roesler, Wilhelm Friedrich, Horst von Bernuth
JournalEuropean journal of pediatrics (Eur J Pediatr) Vol. 166 Issue 8 Pg. 785-8 (Aug 2007) ISSN: 0340-6199 [Print] Germany
PMID17103189 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Genetic Markers
Topics
  • Bone Marrow Transplantation
  • Brain Diseases (diagnosis, etiology, therapy)
  • Cerebrum (pathology)
  • Child
  • Gene Deletion
  • Genetic Markers
  • Granulomatous Disease, Chronic (complications, diagnosis, genetics, therapy)
  • Humans
  • Lung Diseases (diagnosis, etiology, therapy)
  • Magnetic Resonance Imaging
  • Male
  • Tomography, X-Ray Computed

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: