Abstract |
We report on a 6-year-old boy with chronic granulomatous disease (CGD) complicated by chronic inflammatory reactions with formation of large pulmonary granuloma as well as intracerebral lesions. Bone marrow transplantation (BMT) from an unrelated donor led to stable reconstitution, to rapid resolution of pulmonary granuloma, and to rapid resolution of intracerebral lesions.
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Authors | Catharina Schuetz, Manfred Hoenig, Ansgar Schulz, Min Ae Lee-Kirsch, Joachim Roesler, Wilhelm Friedrich, Horst von Bernuth |
Journal | European journal of pediatrics
(Eur J Pediatr)
Vol. 166
Issue 8
Pg. 785-8
(Aug 2007)
ISSN: 0340-6199 [Print] Germany |
PMID | 17103189
(Publication Type: Case Reports, Journal Article)
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Chemical References |
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Topics |
- Bone Marrow Transplantation
- Brain Diseases
(diagnosis, etiology, therapy)
- Cerebrum
(pathology)
- Child
- Gene Deletion
- Genetic Markers
- Granulomatous Disease, Chronic
(complications, diagnosis, genetics, therapy)
- Humans
- Lung Diseases
(diagnosis, etiology, therapy)
- Magnetic Resonance Imaging
- Male
- Tomography, X-Ray Computed
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