[Multiple post-chemotherapy plantar nevi].

Abstract

The induction of multiple melanocytic nevi in children after chemotherapy has been documented in the literature. This situation apparently has more to do with the state of immunosuppression that is produced than with any specific agent used. We present the case of a 12-year-old girl who presented with multiple plantar melanocytic nevi after multidrug chemotherapy for acute lymphocytic leukemia. None of the lesions showed any alarming clinical signs. Although the degeneration of post-chemotherapy melanocytic nevi to melanoma has not been documented in any of the cases described, the presence of a high number of melanocytic nevi is an accepted risk factor for melanoma; thus, close clinical follow-up of these patients seems advisable.

• Authors: Luis Hueso, Celia Requena, Carlos Serra-Guillén, Alberto Alfaro, Eduardo Nagore, Beatriz Llombart, Rafael Botella-Estrada, Onofre Sanmartín, Carlos Guillén
• Journal: Actas dermo-sifiliograficas (Actas Dermosifiliogr) Vol. 97 Issue 5 Pg. 327-9 (Jun 2006) ISSN: 0001-7310 [Print] Spain
• Vernacular Title: Nevos plantares múltiples posquimioterapia.
• PMID: 16956565 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antineoplastic Agents

Topics

• Antineoplastic Agents (adverse effects)
• Child
• Female
• Foot Diseases (chemically induced, pathology)
• Humans
• Nevus, Pigmented (chemically induced, pathology)
• Precursor Cell Lymphoblastic Leukemia-Lymphoma (drug therapy)
• Skin Neoplasms (chemically induced, pathology)