Celiac disease and childhood cancer.

Abstract

Celiac disease is an autoimmune enteropathy developing in genetically predisposed individuals after mucosal contact with gluten, secondary to unknown triggering factors. An increased rate of malignancies in adults with celiac disease has been confirmed in several studies, but there is considerable evidence that a gluten-free diet protects against the development of cancer. The association between celiac disease and childhood cancer is not clear. Few cases are reported in the literature. Here, we report the cases referred to our pediatric oncology unit with a review of the literature.

• Authors: Stefano Cereda, Graziella Cefalo, Filippo Spreafico, Serena Catania, Cristina Meazza, Marta Podda, Monica Terenziani
• Journal: Journal of pediatric hematology/oncology (J Pediatr Hematol Oncol) Vol. 28 Issue 6 Pg. 346-9 (Jun 2006) ISSN: 1077-4114 [Print] United States
• PMID: 16794501 (Publication Type: Case Reports, Journal Article)

Chemical References

• Glutens

Topics

• Autoimmune Diseases (complications, genetics)
• Celiac Disease (complications, genetics)
• Child
• Child, Preschool
• Diet, Atherogenic
• Female
• Genetic Predisposition to Disease
• Glutens
• Humans
• Male
• Neoplasms (etiology, genetics)