[Reserves for enhancing the efficiency of treatment for pulmonary tuberculosis in adolescents].

Abstract

Out of 222 adolescents with pulmonary tuberculosis, 115 received a short-term intensive DOTS chemotherapy and 107 had a conventional triple antibacterial treatment (TAT) regimen. The advantages of intensive chemotherapy were relatively better results with a reduction in the duration of treatment by 1.5-2 months; its disadvantage was more frequent (37.7% versus 18.7%) adverse toxic reactions. The local administration of TAT (lymphotropic as aerosols) promotes a decrease in toxic reactions and an increase in the efficiency of treatment for the destructive and bacillary forms of pulmonary tuberculosis. This is also favored by the timely use of collapse therapy--artificial pneumothorax and pneumoperitoneum (following 1.5-3 months).

• Authors: G K Guseĭnov, Kh Iu Pakhieva, N A Balashova
• Journal: Problemy tuberkuleza i boleznei legkikh (Probl Tuberk Bolezn Legk) Issue 1 Pg. 16-9 ( 2006) ISSN: 1728-2993 [Print] Russia (Federation)
• PMID: 16512179 (Publication Type: Case Reports, English Abstract, Journal Article)

Chemical References

• Antitubercular Agents
• Isoniazid

Topics

• Adolescent
• Antitubercular Agents (therapeutic use)
• Child
• Female
• Humans
• Isoniazid (therapeutic use)
• Male
• Tuberculosis, Pulmonary (drug therapy)