[The question of surgical therapy for necrolytic migratory erythema, a cutaneous disease].

Abstract

Necrolytic migratory erythema (NME) is a rare paraneoplastic dermatologic condition. Its underlying cause is usually a pancreatic islet cell tumour with marked glucagon secretion. The glucagonoma syndrome is characterised by pancreatic neuroendocrine neoplasm, NME, and diabetes mellitus. We present a case of glucagonoma syndrome in a 58-year-old woman with a history of recurrent cutaneous manifestations who was referred for surgical resection of a pancreatic neoplasm after the NME was finally diagnosed. We discuss diagnostic methods, differential diagnosis, and therapeutic management of this disease.

• Authors: R Siegel, R Linse, B Rau
• Journal: Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen (Chirurg) Vol. 77 Issue 6 Pg. 535-8 (Jun 2006) ISSN: 0009-4722 [Print] Germany
• Vernacular Title: Erythema necrolyticum migrans: Chirurgische Therapie einer Hauterkrankung?
• PMID: 16362349 (Publication Type: Case Reports, Comparative Study, Journal Article)

Topics

• Biopsy
• Erythema (etiology, pathology)
• Female
• Follow-Up Studies
• Glucagonoma (complications, diagnosis, diagnostic imaging, surgery)
• Humans
• Middle Aged
• Pancreatectomy
• Pancreatic Neoplasms (classification, complications, diagnostic imaging, surgery)
• Paraneoplastic Syndromes
• Radiography, Abdominal
• Skin (pathology)
• Time Factors
• Tomography, X-Ray Computed
• Treatment Outcome