Splenic accumulation of Tc-99m HMDP in a patient with severe alcoholic cirrhosis of the liver.

Abstract

The authors report unusual splenic accumulation of Tc-99m hydroxymethylene diphosphonate (HMDP) on bone scintigraphy of a patient with alcoholic cirrhosis of the liver. Laboratory studies showed hemolytic anemia and hemochromatosis resulting from alcohol abuse, both of which are thought to be related to the diffuse splenic uptake observed. When diffuse splenic accumulation by Tc-99m HMDP is seen, the existence of alcoholic hepatopathy might be considered.

• Authors: Etsushi Kawamura, Joji Kawabe, Takehiro Hayashi, Ai Oe, Jin Kotani, Kenji Torii, Daiki Habu, Susumu Shiomi
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 30 Issue 5 Pg. 351-2 (May 2005) ISSN: 0363-9762 [Print] United States
• PMID: 15827413 (Publication Type: Case Reports, Journal Article)

Chemical References

• Radiopharmaceuticals
• technetium Tc 99m hydroxymethylene diphosphonate
• Technetium Tc 99m Medronate

Topics

• Humans
• Liver Cirrhosis, Alcoholic (diagnostic imaging, metabolism)
• Male
• Middle Aged
• Radionuclide Imaging
• Radiopharmaceuticals (pharmacokinetics)
• Severity of Illness Index
• Spleen (diagnostic imaging, metabolism)
• Technetium Tc 99m Medronate (analogs & derivatives, pharmacokinetics)