Is immune-mediated complete fetal atrioventricular block reversible by transplacental dexamethasone therapy?

Abstract

We report for the first time a fetal case with sustained regression from isolated complete to first-degree heart block on transplacental treatment with high-dose dexamethasone. Doppler echocardiography is an excellent diagnostic tool in the non-invasive assessment of fetal atrioventricular conduction and its anomalies.

• Authors: E T Jaeggi, E D Silverman, S-J Yoo, J Kingdom
• Journal: Ultrasound in obstetrics & gynecology : the official journal of the International Society of Ultrasound in Obstetrics and Gynecology (Ultrasound Obstet Gynecol) Vol. 23 Issue 6 Pg. 602-5 (Jun 2004) ISSN: 0960-7692 [Print] England
• PMID: 15170804 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright 2004 ISUOG. Published by John Wiley & Sons, Ltd.

Chemical References

• Glucocorticoids
• Dexamethasone

Topics

• Adult
• Dexamethasone (administration & dosage)
• Echocardiography, Doppler (methods)
• Female
• Fetal Blood (physiology)
• Fetal Diseases (diagnostic imaging, drug therapy, physiopathology)
• Glucocorticoids (administration & dosage)
• Heart Block (diagnostic imaging, drug therapy, physiopathology)
• Heart Rate, Fetal (physiology)
• Humans
• Lupus Erythematosus, Systemic (physiopathology)
• Pregnancy
• Prenatal Care (methods)
• Ultrasonography, Prenatal (methods)