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Rituximab-related late-onset neutropenia after autologous stem cell transplantation for aggressive non-Hodgkin's lymphoma.

Abstract
Rituximab, an anti-CD20 monoclonal antibody, is increasingly used in the treatment of B-cell non-Hodgkin's lymphoma. Late-onset neutropenia in relation to rituximab has been recently described. In this report, we present six cases occurring after stem cell transplantation and discuss the potential impact of this complication.
AuthorsB Lemieux, S Tartas, C Traulle, D Espinouse, C Thieblemont, F Bouafia, Q Alhusein, D Antal, G Salles, B Coiffier
JournalBone marrow transplantation (Bone Marrow Transplant) Vol. 33 Issue 9 Pg. 921-3 (May 2004) ISSN: 0268-3369 [Print] England
PMID15034544 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Antibodies, Monoclonal
  • Antibodies, Monoclonal, Murine-Derived
  • Antigens, CD20
  • Antineoplastic Agents
  • Granulocyte Colony-Stimulating Factor
  • Rituximab
Topics
  • Aged
  • Antibodies, Monoclonal (pharmacology)
  • Antibodies, Monoclonal, Murine-Derived
  • Antigens, CD20 (chemistry)
  • Antineoplastic Agents (pharmacology)
  • Female
  • Granulocyte Colony-Stimulating Factor (metabolism)
  • Humans
  • Lymphoma, Non-Hodgkin (therapy)
  • Male
  • Middle Aged
  • Neutropenia (etiology)
  • Neutrophils (metabolism)
  • Rituximab
  • Stem Cell Transplantation
  • Time Factors

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