Fulminant endocarditis due to infection with penicillinase-producing Neisseria gonorrhoeae.

Abstract

Endocarditis is a rare but potentially lethal manifestation of gonococcal infection. We report the case of a patient with fulminant endocarditis secondary to infection with penicillinase-producing Neisseria gonorrhoeae (PPNG). The patient had rapid deterioration from extensive destruction of the aortic valve with abscess and fistula formation. Lifesaving emergency surgery was performed. To our knowledge this is the first reported case of gonococcal endocarditis secondary to infection with a penicillinase-producing organism.

• Authors: P J Weiss, C A Kennedy, D F McCann, H E Hill, E C Oldfield 3rd
• Journal: Sexually transmitted diseases (Sex Transm Dis) 1992 Sep-Oct Vol. 19 Issue 5 Pg. 288-90 ISSN: 0148-5717 [Print] United States
• PMID: 1411846 (Publication Type: Case Reports, Journal Article)

Chemical References

• Penicillinase

Topics

• Adult
• Aortic Diseases (etiology)
• Bacteremia (drug therapy, microbiology)
• Endocarditis, Bacterial (complications, drug therapy, microbiology)
• Fistula (etiology)
• Gonorrhea (drug therapy, microbiology)
• Heart Atria
• Heart Diseases (etiology)
• Humans
• Male
• Neisseria gonorrhoeae (enzymology, isolation & purification)
• Penicillinase (metabolism)