[Blastocystosis: nitazoxanide as a new therapeutic option].

Abstract

We report a case of a patient with AIDS and severe immunosuppression who developed diarrhea due to a vacuolar stage of Blastocystis hominis. The patient was treated with nitazoxanide, a 5-nitrothiazole broad-spectrum antiparasitic agent. We obtained complete remission of symptoms and eradication of the parasite. Nitazoxanide is a new treatment option for blastocystosis in AIDS patients. Further studies to test its efficacy are needed.

• Authors: Sérgio Cimerman, Maria Cecília Teixeira Ladeira, Wilma Assunção Iuliano
• Journal: Revista da Sociedade Brasileira de Medicina Tropical (Rev Soc Bras Med Trop) 2003 May-Jun Vol. 36 Issue 3 Pg. 415-7 ISSN: 0037-8682 [Print] Brazil
• Vernacular Title: Blastocistose: nitazoxanida como nova opção terapêutica.
• PMID: 12908045 (Publication Type: Case Reports, Journal Article)

Chemical References

• Antiprotozoal Agents
• Nitro Compounds
• Thiazoles
• nitazoxanide

Topics

• AIDS-Related Opportunistic Infections (diagnosis, drug therapy)
• Adult
• Animals
• Antiprotozoal Agents (therapeutic use)
• Blastocystis Infections (diagnosis, drug therapy)
• Blastocystis hominis (isolation & purification)
• Feces (parasitology)
• Humans
• Male
• Nitro Compounds
• Parasite Egg Count
• Thiazoles (therapeutic use)