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Treatment of pustular psoriasis with granulocyte and monocyte adsorption apheresis.

Abstract
We studied the efficacy of granulocyte and monocyte adsorption apheresis in 2 patients with pustular psoriasis, one localized, the other generalized. Treatment with granulocyte and monocyte adsorption apheresis resulted in remarkable clearing of the skin lesions, suggesting that this therapy is a valuable tool for treating patients with intractable skin diseases attributable to activated granulocytes. We present detailed descriptions of these patients and this novel therapy.
AuthorsTakuro Kanekura, Noriko Yoshii, Tomokazu Yonezawa, Hisashi Kawabata, Hiroshi Saruwatari, Tamotsu Kanzaki
JournalJournal of the American Academy of Dermatology (J Am Acad Dermatol) Vol. 49 Issue 2 Pg. 329-32 (Aug 2003) ISSN: 0190-9622 [Print] United States
PMID12894091 (Publication Type: Case Reports, Journal Article)
Topics
  • Female
  • Granulocytes
  • Humans
  • Leukapheresis (instrumentation, methods)
  • Male
  • Middle Aged
  • Monocytes
  • Psoriasis (pathology, therapy)

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