Vaginoplasty with Interceed absorbable adhesion barrier for complete squamous epithelialization in vaginal agenesis.

Abstract

OBJECTIVE:

The purpose of this study was to present our experiences of an innovative surgical approach for vaginal agenesis with the use of Interceed absorbable adhesion barrier (Ethicon) to achieve a satisfactory neovagina.

STUDY DESIGN:

The current study involved 10 subjects who were diagnosed with vaginal agenesis. After the creation of a vaginal tunnel, a mold that had been wrapped with Interceed was placed in the neovagina.

RESULTS:

No operative and postoperative complications were encountered. The duration of the operation was < or =30 minutes, and blood loss was minimal. The postoperative hospital stay was only 2 days. Epithelialization of the neovagina was achieved 1 to 4 months after the operation, and all patients were satisfied with the outcome. The neovagina that was created with this procedure was not much different from the normal adult vagina as far as histologic and physiologic conditions are concerned.

CONCLUSION:

This innovative surgical procedure may be a potential alternative approach for the therapy of vaginal agenesis with the use of the absorbable adhesion barrier Interceed with excellent results.

• Authors: Satoru Motoyama, Jovelle B Laoag-Fernandez, Shinsuke Mochizuki, Shingo Yamabe, Takeshi Maruo
• Journal: American journal of obstetrics and gynecology (Am J Obstet Gynecol) Vol. 188 Issue 5 Pg. 1260-4 (May 2003) ISSN: 0002-9378 [Print] United States
• PMID: 12748495 (Publication Type: Journal Article)

Chemical References

• Cellulose, Oxidized
• INTERCEED

Topics

• Adolescent
• Adult
• Cellulose, Oxidized (therapeutic use)
• Epithelium (growth & development, pathology)
• Female
• Humans
• Length of Stay
• Patient Satisfaction
• Stents
• Surgically-Created Structures
• Tissue Adhesions (prevention & control)
• Treatment Outcome
• Vagina (abnormalities, pathology, surgery)