Abstract | PURPOSE: DESIGN: Prospective, randomized, double-masked crossover active controlled comparison. METHODS: We evaluated conjunctival hyperemia by a standard photographic measure at the slit lamp and by anterior segment photographs in healthy subjects after dosing for 5 days with latanoprost, bimatoprost, or travoprost. Conjunctival hyperemia was evaluated at 24-hour trough (hour 0) and at hour 1 after dosing. Each subject was crossed over between periods after a 1-week washout interval. RESULTS: CONCLUSIONS:
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Authors | William C Stewart, Allan E Kolker, Jeanette A Stewart, Jessica Leech, Angi L Jackson |
Journal | American journal of ophthalmology
(Am J Ophthalmol)
Vol. 135
Issue 3
Pg. 314-20
(Mar 2003)
ISSN: 0002-9394 [Print] United States |
PMID | 12614748
(Publication Type: Clinical Trial, Comparative Study, Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Copyright | Copyright 2003 by Elsevier Science Inc. |
Chemical References |
- Amides
- Antihypertensive Agents
- Lipids
- Prostaglandins F, Synthetic
- Cloprostenol
- Latanoprost
- Bimatoprost
- Travoprost
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Topics |
- Adult
- Amides
- Antihypertensive Agents
(administration & dosage, adverse effects)
- Bimatoprost
- Cloprostenol
(administration & dosage, adverse effects, analogs & derivatives)
- Conjunctiva
(blood supply, drug effects)
- Conjunctival Diseases
(chemically induced, physiopathology)
- Cross-Over Studies
- Double-Blind Method
- Female
- Humans
- Hyperemia
(chemically induced, physiopathology)
- Intraocular Pressure
(drug effects)
- Latanoprost
- Lipids
(administration & dosage, adverse effects)
- Male
- Prospective Studies
- Prostaglandins F, Synthetic
(administration & dosage, adverse effects)
- Time Factors
- Travoprost
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