Abstract | OBJECTIVE: METHODS:
Music therapy combined with anti- tumor drugs, including chemotherapy and Chinese drugs, was given to 162 tumor patients according to syndrome differentiation to observe the change of self-rating depression scale (SDS), self-rating anxiety scale (SAS), minnesota multiphasic personality inventory (MMPI), Hamilton rating scale for depression (HAMD) and T lymphocyte subsets (immuno-histochemical assay), NK cell anti- tumor activity (NAG method), etc. while 46 caces didn't receive music therapy were taken as the control group. RESULTS: The scale marks of SDS and SAS of the treated group after treatment were obviously lower than that of the control group significantly (P < 0.05, P < 0.01). After treatment, the average values of MMPI on falseness (F), hypochondriasis (HS), depression (D) and psychosthenia (Pt) in the treated group were all improved (P < 0.01 or P < 0.05); but in the control group, significant difference only showed in MMPI on HS (P < 0.05). HAMD in the treated group revealed some improvement in insomnia, early awakening, daily work and interest, systemic symptoms and hypochondriasis (P < 0.05), and significant improvement in depression, difficulty in falling asleep, psychiatric anxiety and somatic anxiety (P < 0.01); while in the control group, only work interest and HS had some improvement (P < 0.05). CD8 percent was reduced in both groups after treatment (P < 0.01), but in the treated group CD3, CD4 and CD4/CD8 ratio were not significantly changed after treatment (P > 0.05); while in the control group they lowered obviously (P < 0.05). As for NK cell anti- tumor activity in the treated group before and after treatment, it was not significantly lowered (P > 0.05); while in the control group the lowering after treatment was significant (P < 0.05). CONCLUSION:
Music therapy could regulate the emotion of tumor patient, optimize the emotional effect, improve the somatic symptoms, enhance the immune function, motivate the active principle and raise the self-regulating power in the body.
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Authors | G R Cai, P W Li, L P Jiao |
Journal | Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
(Zhongguo Zhong Xi Yi Jie He Za Zhi)
Vol. 21
Issue 12
Pg. 891-4
(Dec 2001)
ISSN: 1003-5370 [Print] China |
PMID | 12575587
(Publication Type: Clinical Trial, English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Drugs, Chinese Herbal
- Etoposide
- Cisplatin
- Fluorouracil
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Topics |
- Adult
- Aged
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Cisplatin
(administration & dosage)
- Drugs, Chinese Herbal
(therapeutic use)
- Etoposide
(administration & dosage)
- Female
- Fluorouracil
(administration & dosage)
- Humans
- Lung Neoplasms
(therapy)
- Male
- Middle Aged
- Music Therapy
- Phytotherapy
- Stomach Neoplasms
(therapy)
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