Tc-99m-tetrofosmin thyroid scan in patients with low I-131 thyroid uptake.

Abstract

UNLABELLED:

Low 24-hour thyroid uptake of I-131 (I-131 uptake) is a common finding that influences evaluation of the thyroid gland.

METHODS:

We studied 20 female patients aged 16-82 years with low I-131 uptake. The following causes of reduced I-131 uptake were defined as (A) six cases with subacute thyroiditis, (B) seven cases with T4 suppression therapy, and (C) seven cases with iodinated pharmaceuticals use. Thirty-minute Tc-99m tetrofosmin thyroid scan was performed within 24 hours of the I-131 thyroid study.

RESULTS:

The results were correlated with neck ultrasound, serum TSH and biopsy histopathological findings. Tc-99m tetrofosmin thyroid scans revealed 10 normal thyroids, five diffuse goiters, four multinodular goitres, and one solitary thyroid nodule.

CONCLUSIONS:

Our results suggest that Tc-99m tetrofosmin thyroid scans may provide additional information to diagnose thyroid pathology in patients with low 24-hour I-131 uptake.

• Authors: Tzu-Yuan Wang, Hurng-Sheng Wu, Cheng Chieh Lin, Cheng Chun Lee, Chia-Hung Kao
• Journal: Endocrine research (Endocr Res) Vol. 28 Issue 3 Pg. 231-8 (Aug 2002) ISSN: 0743-5800 [Print] England
• PMID: 12489572 (Publication Type: Journal Article)

Chemical References

• Iodine Radioisotopes
• Organophosphorus Compounds
• Organotechnetium Compounds
• Radiopharmaceuticals
• technetium tc-99m tetrofosmin
• Iodine

Topics

• Adolescent
• Adult
• Aged
• Aged, 80 and over
• Female
• Humans
• Iodine (pharmacokinetics)
• Iodine Radioisotopes
• Middle Aged
• Organophosphorus Compounds
• Organotechnetium Compounds
• Radionuclide Imaging
• Radiopharmaceuticals
• Thyroid Diseases (diagnostic imaging, metabolism)
• Thyroid Gland (diagnostic imaging, metabolism)