Sisomicin in urinary tract infection: Tolerance and efficacy study.

Abstract

Twenty-one patients with gram-negative urinary tract infections were treated with sisomicin, a new aminoglycoside antibiotic. Bacteriologic cure was achieved in 62 per cent of patients, and improvement in another 33 per cent. Mild transient elevation of serum creatinine occurred in 3 patients. No other toxicity was observed. Further clinical trials with more frequent dose administration and in combination with other antibiotics is suggested.

• Authors: W Etra, M Surgalla, Z Wajsman, G Baumgartner, C Merrin
• Journal: Urology (Urology) Vol. 7 Issue 2 Pg. 160-4 (Feb 1976) ISSN: 0090-4295 [Print] United States
• PMID: 1246785 (Publication Type: Journal Article)

Chemical References

• Anti-Bacterial Agents
• Sisomicin

Topics

• Adult
• Anti-Bacterial Agents (therapeutic use)
• Enterobacteriaceae Infections (drug therapy)
• Humans
• Pseudomonas Infections (drug therapy)
• Sisomicin (therapeutic use)
• Urinary Tract Infections (complications, drug therapy)