HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Tailored approach to Zenker's diverticula.

AbstractBACKGROUND:
Zenker's diverticula (ZD) can be treated by diverticulostomy or open surgery (upper esophageal sphincter myotomy and diverticulectomy or diverticulopexy). The aim of this study was to compare the outcome of the two alternative treatments.
METHODS:
Fifty eight patients were scored for symptoms and upper esophageal sphincter (UES) pressure; relaxations and intrabolus pressures were recorded by manometry. Treatment depended on operative risk and ZD size. Twenty four patients with high surgical risk and/or a <3-cm or >5-cm pouch underwent diverticulostomy; the other 34 had open surgery.
RESULTS:
Mortality was nil. Five patients had postoperative complications after open surgery (p<0.05). Hospital stay was shorter after diverticulostomy (p<0.001). Follow-up (41 months; range, 1-101) was obtained in 53 patients. Postoperative manometry showed a UES pressure reduction, improved UES relaxation, and lower intrabolus pressure in both groups (p<0.05). In the diverticulostomy group, three patients complained of severe dysphagia. vs none in the open surgery group (p<0.05).
CONCLUSION:
Diverticulostomy is safe, quick, and effective for most patients with medium-sized ZD, but open surgery offers better long-term results and should be recommended for younger, healthy patients with small or very large diverticula.
AuthorsG Zaninotto, S Narne, M Costantini, D Molena, C Cutrone, G Portale, M Costantino, C Rizzetto, U Basili, E Ancona
JournalSurgical endoscopy (Surg Endosc) Vol. 17 Issue 1 Pg. 129-33 (Jan 2003) ISSN: 1432-2218 [Electronic] Germany
PMID12370775 (Publication Type: Clinical Trial, Comparative Study, Journal Article)
Topics
  • Adult
  • Aged
  • Aged, 80 and over
  • Esophagus (physiopathology)
  • Female
  • Follow-Up Studies
  • Gastroscopy (methods)
  • Humans
  • Length of Stay
  • Male
  • Manometry (methods)
  • Middle Aged
  • Surgical Stapling
  • Treatment Outcome
  • Zenker Diverticulum (physiopathology, surgery)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: