Intracoronary stent implantation under intracoronary ultrasound guidance with aspirin and ticlopidine therapy.

Abstract

OBJECTIVE:

To observe the immediate angiographic and intravascular ultrasound (IVUS) results and their effects on one month clinical outcomes in forty-one patients who submitted to coronary stent deployment with IVUS guidance.

METHODS:

All patients were allocated to coronary stent implantation with high inflation pressure. After good angiographic results (< 20% residual stenosis), all patients underwent IVUS and higher-pressure dilatation would be necessary if criteria for optimal coronary stent implantation were not met. The optimal criterion of IVUS for stent implantation was the ratio of intrastent lumen cross-sectional area to the average of the proximal and distal reference lumen cross-sectional areas > or = 80%. All patients had aspirin and ticlopidine therapy on the day of angioplasty and during the one month follow-up period.

RESULTS:

Optimal criteria of IVUS were obtained without any further intrastent dilatation in twenty-five patients but intrastent higher-pressure dilatation was performed in fourteen patients whose ultrasound results did not reach the criteria. In these patients, we increased the minimal intrastent lumen area 25.7% (P < 0.05). Thirty-five patients (90%) had good minimal intrastent lumen area of IVUS. There were no deaths, myocardial infarction, acute stent thrombosis or need for revascularization during the study and the one month follow-up.

CONCLUSIONS:

Intracoronary stent deployment under IVUS guidance, including combining aspirin and ticlopidine therapy, had beneficial ultrasound results and good clinical outcomes after one month follow-up.

• Authors: D Zhang, X Cai, W Shen, F Schiele, J P Bassand
• Journal: Chinese medical journal (Chin Med J (Engl)) Vol. 114 Issue 3 Pg. 262-5 (Mar 2001) ISSN: 0366-6999 [Print] China
• PMID: 11780310 (Publication Type: Journal Article)

Chemical References

• Fibrinolytic Agents
• Ticlopidine
• Aspirin

Topics

• Aged
• Angioplasty, Balloon, Coronary
• Aspirin (therapeutic use)
• Combined Modality Therapy
• Coronary Disease (diagnostic imaging, drug therapy, therapy)
• Female
• Fibrinolytic Agents (therapeutic use)
• Follow-Up Studies
• Humans
• Male
• Middle Aged
• Stents
• Ticlopidine (therapeutic use)
• Treatment Outcome
• Ultrasonography, Interventional (methods)