[Features of clinical course and proteinase inhibitor balance in tears in eye burns of different localization (an experimental study)].

Abstract

Chemical burns of the eye of different location (cornea, corneal fragment with adjacent conjunctiva, and limbus) were studied in experiments. Clinical picture and changes in the lacrimal proteinase inhibitor balance were analyzed. Burn disease is less severe and the number of complications is less if a fragment of the cornea with adjacent conjunctiva and a fragment of the limbus are injured than in case of a corneal burn of the same depth and area. Burn of the total limbus area is a severe injury involving essential shifts in the proteinase inhibitor balance, leading to deep organic changes in the cornea and inner structures of the eye, eventuating in its subatrophy.

• Authors: N B Chesnokova, P V Malarpv, O V Beznos
• Journal: Vestnik oftalmologii (Vestn Oftalmol) 2001 Mar-Apr Vol. 117 Issue 2 Pg. 38-40 ISSN: 0042-465X [Print] Russia (Federation)
• Vernacular Title: Osobennosti klinicheskogo techeniia i proteinazno-ingibitornogo balansa v sleze pri ozhogakh glaz razlichnoĭ lokalizatsii (éksperimental'noe issledovanie).
• PMID: 11510165 (Publication Type: Comparative Study, English Abstract, Journal Article)

Chemical References

• Protease Inhibitors

Topics

• Animals
• Burns, Chemical (metabolism, pathology)
• Conjunctiva (injuries, pathology)
• Cornea (pathology)
• Corneal Injuries
• Eye Burns (chemically induced, metabolism, pathology)
• Protease Inhibitors (metabolism)
• Rabbits
• Tears (metabolism)
• Time Factors