Loss of E-cadherin is the fundamental defect in diffuse-type gastric carcinoma and infiltrating lobular carcinoma of the breast.

• Authors: J K Chan, C S Wong
• Journal: Advances in anatomic pathology (Adv Anat Pathol) Vol. 8 Issue 3 Pg. 165-72 (May 2001) ISSN: 1072-4109 [Print] United States
• PMID: 11345240 (Publication Type: Journal Article)

Chemical References

• Cadherins
• DNA, Neoplasm

Topics

• Adenocarcinoma (genetics, metabolism, pathology)
• Breast Neoplasms (genetics, metabolism, pathology)
• Cadherins (genetics, metabolism)
• Carcinoma, Lobular (genetics, metabolism, pathology)
• DNA, Neoplasm (analysis)
• Female
• Genetic Predisposition to Disease
• Humans
• Loss of Heterozygosity
• Male
• Point Mutation
• Polymerase Chain Reaction
• Stomach Neoplasms (genetics, metabolism, pathology)