Abstract | OBJECTIVE: The aim of the study was to determine the clinical profile, aetiology and radiological categories in children diagnosed with bronchiolitis obliterans (BO). METHODOLOGY: We undertook a review of the medical records and radiological studies of 14 children with BO. RESULTS: Unresolving cough and wheeze after a short respiratory illness was the commonest presentation. A viral pneumonitis was identified as the initial respiratory event prior to the development of BO in six children and Mycoplasma pneumoniae was the cause in another three children. Chest X-ray findings could be divided into four distinct patterns that were hyperinflation (n=5), mixed pattern of atelectasis, hyperlucency and bronchial thickening (n=4), unilateral small hyperlucent lung (n=3) and unilateral collapse of one lung (n=2). High resolution computed tomogram (HRCT) chest showing areas of hyperaeration and mosaic ground glass patterns with bronchial thickening were commonly found in patients whose chest X-ray showed bilateral changes. Patients with bilateral lung changes were more likely to have failure to thrive and persistent respiratory symptoms on follow up. CONCLUSION: A diagnosis of BO can be made from typical clinical features combined with an understanding of the different chest X-ray categories and HRCT of the chest. A viral aetiology was the commonest cause for BO in our series.
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Authors | P W Chan, R Muridan, J A Debruyne |
Journal | Respirology (Carlton, Vic.)
(Respirology)
Vol. 5
Issue 4
Pg. 369-75
(Dec 2000)
ISSN: 1323-7799 [Print] Australia |
PMID | 11192548
(Publication Type: Journal Article)
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Topics |
- Adolescent
- Bronchiolitis Obliterans
(diagnostic imaging, etiology)
- Child
- Child, Preschool
- Cough
(etiology)
- Failure to Thrive
(etiology)
- Female
- Hospitalization
- Humans
- Infant
- Malaysia
- Male
- Pneumonia
(complications, microbiology)
- Respiratory Sounds
(etiology)
- Retrospective Studies
- Tomography, X-Ray Computed
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