[Intravenous mogadon in epileptic patients. Clinico-electroencephalographic study].

Abstract

Mogadon as a parenteral solution was employed for treating status epilepticus (15 cases), intermitent epileptic seizures (10 cases), Lennox syndrome (14 cases), myoclonic seizures (5 cases) and absences (6 cases). The dosage layed between 3,3 mg and 10 mg according to each individual case. Status epilepticus and intermitent seizures disappeared following the injection and so did the irritative EEG alterations. Remission was observed in 10 Lennox cases while the remaining 4 improved. Mogadon abolished myoclonic seizures, in some cases beyond 6 hours. In simple absence improvement was also evident, although more shortlived than in myoclonic seizures. Sleepiness was side-effect, occurring in some cases.

• Authors: R S de Oliveira
• Journal: Arquivos de neuro-psiquiatria (Arq Neuropsiquiatr) Vol. 37 Issue 1 Pg. 48-52 (Mar 1979) ISSN: 0004-282X [Print] Germany
• Vernacular Title: Mogadon endovenoso em pacientes epilépticos. Estudo clínico-eletrencefalográfico.
• PMID: 111652 (Publication Type: English Abstract, Journal Article)

Chemical References

• Nitrazepam

Topics

• Electroencephalography
• Epilepsies, Myoclonic (drug therapy)
• Epilepsies, Partial (drug therapy)
• Epilepsy (drug therapy)
• Epilepsy, Absence (drug therapy)
• Female
• Humans
• Infusions, Parenteral
• Male
• Nitrazepam (administration & dosage, pharmacology, therapeutic use)
• Status Epilepticus (drug therapy)