Surgical results for small cell lung cancer based on the new TNM staging system. Thoracic Surgery Study Group of Osaka University, Osaka, Japan.

Abstract

BACKGROUND:

Operation with combined chemotherapy has been recently recommended for very early stage of small cell lung cancer without lymph node metastasis.

METHODS:

A retrospective study was undertaken in 91 patients who had undergone pulmonary resection for small cell lung cancer according to the new international staging system.

RESULTS:

The 5-year overall probability of survival was 37.1%. The 5-year survival rate was 100% for p-stage 0, 56.1% for p-stage IA, 30.0% for p-stage IB, 57.1% for p-stage IIA, and 42.9% for p-stage IIB. In the p-stage IA-IIB patients who underwent a complete resection, the 5-year survival rate of the patients treated by operation with chemotherapy was better than that of patients treated by operation alone. In addition, the 5-year survival rate of the patients who had four or more courses of chemotherapy was 80.0%.

CONCLUSIONS:

These results suggest that operation should be considered for p-stage IA-IIB patients and more than four courses of combined chemotherapy might be desirable in these resectable cases.

• Authors: M Inoue, S Miyoshi, T Yasumitsu, T Mori, K Iuchi, H Maeda, H Matsuda
• Journal: The Annals of thoracic surgery (Ann Thorac Surg) Vol. 70 Issue 5 Pg. 1615-9 (Nov 2000) ISSN: 0003-4975 [Print] Netherlands
• PMID: 11093496 (Publication Type: Journal Article)

Topics

• Adult
• Aged
• Aged, 80 and over
• Carcinoma, Small Cell (mortality, pathology, surgery)
• Combined Modality Therapy
• Female
• Humans
• Lung Neoplasms (mortality, pathology, surgery)
• Male
• Middle Aged
• Neoplasm Staging (methods)
• Pneumonectomy
• Retrospective Studies
• Survival Rate
• Treatment Outcome