Malignant osteopetrosis obscured by maternal vitamin D deficiency in a neonate.

Abstract

UNLABELLED:

A neonate presented with clinical, biochemical, endocrine and radiographic features consistent with vitamin D deficiency rickets of maternal origin. Persistent hypocalcemia and subsequent development of pancytopenia, hemolysis and hepatosplenomegaly prompted further studies that led to the diagnosis of infantile osteopetrosis.

CONCLUSION:

Osteopetrosis is an important differential diagnosis of neonatal rickets and is not excluded by low vitamin D levels.

• Authors: D Popp, B Zieger, A Schmitt-Gräff, W Nützenadel, F Schaefer
• Journal: European journal of pediatrics (Eur J Pediatr) Vol. 159 Issue 6 Pg. 412-5 (Jun 2000) ISSN: 0340-6199 [Print] Germany
• PMID: 10867844 (Publication Type: Case Reports, Journal Article)

Topics

• Female
• Humans
• Infant, Newborn
• Male
• Osteopetrosis (etiology)
• Pregnancy
• Pregnancy Complications
• Vitamin D Deficiency