Abstract | OBJECTIVE: The purpose of this study was to evaluate the value of activation mapping for radiofrequency modification of the sinus node and the long-term success rate of the procedure in a series of patients with inappropriate sinus tachycardia. BACKGROUND: METHODS: RESULTS: The ablation procedure was successful acutely in reducing the baseline sinus rate to <90/min and the sinus rate during isoproterenol infusion by >20% in 22 of 29 patients (76%). In 13 of 22 patients (59%) with a successful acute outcome, successive applications of radiofrequency energy at the site of earliest endocardial activation resulted in a cranial-caudal migration of earliest endocardial activation from the high lateral right atrium, along with a step-wise reduction in heart rate. In the other nine patients (41%) with a successful acute outcome, the reduction in sinus rate occurred abruptly, unaccompanied by migration of the site of earliest activation. Symptoms due to inappropriate sinus tachycardia recurred at a mean of 4.4+/-; 3 months after the ablation procedure in 6 of 22 patients (27%). After additional procedures in three patients, symptoms of inappropriate sinus tachycardia ultimately were successfully eliminated over the long-term in 19 of 29 patients (66%). CONCLUSIONS:
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Authors | K C Man, B Knight, H F Tse, F Pelosi, G F Michaud, M Flemming, S A Strickberger, F Morady |
Journal | Journal of the American College of Cardiology
(J Am Coll Cardiol)
Vol. 35
Issue 2
Pg. 451-7
(Feb 2000)
ISSN: 0735-1097 [Print] United States |
PMID | 10676693
(Publication Type: Comparative Study, Journal Article)
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Topics |
- Action Potentials
- Adult
- Aged
- Body Surface Potential Mapping
(methods)
- Catheter Ablation
- Female
- Heart Rate
- Humans
- Male
- Middle Aged
- Recurrence
- Reoperation
- Tachycardia, Sinus
(physiopathology, surgery)
- Treatment Outcome
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