Abstract |
Glycyrramum was shown to potentiate the antitumor and antimetastatic effects of cyclophosphamide treatment in mice and rats with transplantable tumors. It also decreased its myelotoxicity. After primary Lewis lung carcinoma was removed glycyrramum treatment significantly inhibited metastacizing processes in mice.
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Authors | T G Razina, E P Zueva, E N Amosova, V V Zhdanov |
Journal | Voprosy onkologii
(Vopr Onkol)
Vol. 45
Issue 5
Pg. 554-6
( 1999)
ISSN: 0507-3758 [Print] Russia (Federation) |
Vernacular Title | Glitsiram kak sredstvo povysheniia èffektivnosti khimioterapii i khirurgicheskogo metoda lecheniia èksperimental'nykh opukholeÄ. |
PMID | 10629717
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Antineoplastic Agents
- Antineoplastic Agents, Alkylating
- Cyclophosphamide
- Glycyrrhetinic Acid
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Topics |
- Animals
- Antineoplastic Agents
(pharmacology)
- Antineoplastic Agents, Alkylating
(pharmacology)
- Carcinoma, Lewis Lung
(drug therapy, prevention & control, secondary, surgery)
- Cyclophosphamide
(pharmacology)
- Drug Synergism
- Female
- Glycyrrhetinic Acid
(pharmacology)
- Mice
- Mice, Inbred C57BL
- Rats
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