Filaricides

05/01/1990 - "The leaf-monkeys, Presbytis cristata and Presbytis melalophos, experimentally infected with subperiodic Brugia malayi, have been used for studies on the pathoimmunology of the infection and the screening of potential filaricides during the last 6-8 years, and considerable information on the pattern of microfilaraemia and adult worm recoveries have been obtained. "
02/01/1991 - "pahangi infections in the dog or cat for the secondary screening, of potential filaricides. "
01/01/1971 - "Comparative studies of the chemotherapeutic activity of various filaricides were carried out and the results in Litomosoides carinii infections of Mastomys natalensis were analysed with special reference to macrofilaricidal activity. "
03/01/1991 - "The Presbytis cristata--Brugia malayi model, now established as a reliable non-human primate model for the experimental screening of potential filaricides, was monitored at monthly intervals for changes in the liver and renal function tests and also for alkaline phosphatase levels during infection. "
06/01/1990 - "The known filaricides, suramin and diethylcarbamazine citrate, were tested against subperiodic Brugia malayi infection in the leaf-monkey, Presbytis cristata. "

11/13/2021 - "Molecular Docking Simulation Studies Identifies Potential Natural Product Derived-Antiwolbachial Compounds as Filaricides against Onchocerciasis."
11/13/2021 - "The six natural products are potential novel antiwolbachial agents with insignificant toxicities which can be explored further as filaricides for onchocerciasis."
05/01/1990 - "[The research of filaricides for the control of african onchocerciasis]."

09/01/1984 - "Studies of potential filaricides: Part 14--Activity of 1-iso-butoxycarbonyl-4-methylpiperazine against experimental filariasis."
01/01/1962 - "Although the etiological agent and the vector of filariasis were recognized early in the history of tropical medicine, control programmes were slow in developing, mainly because efficient filaricides were not known. "

08/01/1990 - "Further work on the chemotherapy of loiasis in monkeys, using DEC and other filaricides, might improve the treatment of this disease."

02/01/1991 - "Although more than 30 potential filaricides have been evaluated in the tertiary screen, only a few compounds have shown some promise against lymphatic filariasis. "