LY2365109

a selective glycine transporter 1 (GlyT1) inhibitor; structure in first source

Also Known As:

((2-(4-benzo(1,3)dioxol-5-yl-2-tert-butylphenoxy)ethyl)methylamino)acetic acid

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

1.	Seizures (Absence Seizure) 12/01/2015 - "Importantly, chronic seizures in the mouse model of TLE were robustly suppressed by systemic administration of the GlyT1 inhibitor LY2365109. "
2.	Epilepsy (Aura) 12/01/2015 - "In support of a role of dysfunctional glycine signaling in the pathophysiology of epilepsy, both the genetic deletion of GlyT1 in hippocampus and the GlyT1 inhibitor LY2365109 increased seizure thresholds in mice. "

1.	Glycine (Aminoacetic Acid)