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seliforant

a selective H4 receptor antagonist

Also Known As:

2-isobutyl-6-(3 methylamino) azetidin-1-yl) pyrimidin-4-amine; SENS-111

Networked: 3 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrimidines: 510
    - seliforant: 3
  - Azetines
    - Azetidines: 6
      - seliforant: 3

Experts

1.	Wersinger, Eric: 2 articles (01/2020 - 12/2018)
2.	Delgado Betancourt, Viviana: 1 article (01/2020)
3.	Dyhrfjeld-Johnsen, Jonas: 1 article (01/2020)
4.	Gueguen, Cindy: 1 article (01/2020)
5.	Petremann, Mathieu: 1 article (01/2020)
6.	Attali, Pierre: 1 article (12/2018)
7.	Gomeni, Roberto: 1 article (12/2018)
8.	Poli, Sonia: 1 article (12/2018)
9.	Schmerber, Sebastien: 1 article (12/2018)
10.	Venail, Frédéric: 1 article (12/2018)

Related Diseases

1.

Vertigo (Positional Vertigo)

12/01/2018 - "SENS-111 did not significantly impact nystagmus but significantly improved latency of vertigo appearance/disappearance, duration and European Evaluation of Vertigo questionnaire parameters vs. baseline. "
12/01/2018 - "Effects of SENS-111 on nystagmus and vertigo induced by modified caloric tests were measured in the MAD studies. "
01/01/2020 - "The effects of SENS-111, a selective oral H4 receptor antagonist with high affinity to both animal and human receptors, on vertigo symptoms was evaluated in a translational in vivo model of unilateral vestibular loss. "
10/06/2016 - "The Effects of SENS-111, A New H4R Antagonist, On Vertigo Induced by Caloric Test in Healthy Volunteers (HV) is Related to Plasma Concentrations."