Akio Shimizu Selected Research

Netrin-1

1/2013

Netrin-1 promotes glioblastoma cell invasiveness and angiogenesis by multiple pathways including activation of RhoA, cathepsin B, and cAMP-response element-binding protein.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Akio Shimizu Research Topics

Disease

20	Neoplasms (Cancer) 12/2023 - 11/2004
10	Deglutition Disorders (Dysphagia) 01/2024 - 05/2010
9	Neoplasm Metastasis (Metastasis) 10/2021 - 11/2004
7	Frailty 02/2024 - 05/2022
5	Malnutrition (Nutritional Deficiencies) 02/2023 - 12/2019
5	Sarcopenia 10/2022 - 05/2018
3	Hemorrhagic Fever with Renal Syndrome (HFRS) 02/2024 - 12/2022
3	Stroke (Strokes) 04/2022 - 12/2021
3	Glioblastoma (Glioblastoma Multiforme) 05/2014 - 05/2011
3	Melanoma (Melanoma, Malignant) 05/2011 - 08/2010
2	Anorexia 12/2023 - 03/2022
2	Inflammation (Inflammations) 10/2022 - 01/2016
2	Edema (Dropsy) 05/2022 - 10/2019
2	Fibrosis (Cirrhosis) 11/2017 - 01/2017
2	Brain Neoplasms (Brain Tumor) 01/2013 - 02/2012
1	Pancreatic Neoplasms (Pancreatic Cancer) 02/2024
1	Ischemic Stroke 12/2023
1	Colorectal Neoplasms (Colorectal Cancer) 01/2023
1	Ileus 01/2023
1	Weight Loss (Weight Reduction) 01/2023
1	Hyperlipoproteinemia Type II (Familial Hypercholesterolemia) 01/2023
1	Cachexia 01/2023
1	Cardiovascular Diseases (Cardiovascular Disease) 01/2023
1	Pneumonia (Pneumonitis) 12/2022
1	Chronic Obstructive Pulmonary Disease (COPD) 11/2022
1	Abdominal Aortic Aneurysm 10/2022
1	Head and Neck Neoplasms (Head and Neck Cancer) 05/2022
1	Cranial Nerve Diseases (Cranial Nerve Disorders) 10/2021
1	Velopharyngeal Insufficiency 10/2021
1	Dysarthria (Spastic Dysarthria) 10/2021
1	Osteoporosis 01/2021
1	Metabolic Bone Diseases (Osteopenia) 01/2021
1	Brugada Syndrome 01/2020
1	Kallmann Syndrome (Kallmann's Syndrome) 01/2020
1	Anosmia 01/2020
1	Hypogonadism (Hypergonadotropic Hypogonadism) 01/2020
1	Atrial Fibrillation 01/2019
1	Bradycardia 01/2019
1	Prostatic Neoplasms (Prostate Cancer) 10/2018
1	Heart Failure 11/2017
1	Cardiomegaly (Heart Hypertrophy) 11/2017
1	Left Ventricular Dysfunction 11/2017
1	Virus Diseases (Viral Diseases) 02/2016
1	Esophageal Squamous Cell Carcinoma 01/2016
1	Hypertension (High Blood Pressure) 01/2016
1	Adenocarcinoma 01/2016
1	Carcinogenesis 01/2016
1	Carcinoma (Carcinomatosis) 01/2016
1	Skin Neoplasms (Skin Cancer) 07/2015
1	Non-alcoholic Fatty Liver Disease 06/2015
1	Liver Diseases (Liver Disease) 06/2015
1	Fatty Liver 06/2015

Drug/Important Bio-Agent (IBA)

7	Proteins (Proteins, Gene)FDA Link 10/2022 - 01/2008
7	Semaphorins (Semaphorin)IBA 05/2014 - 11/2004
4	Biomarkers (Surrogate Marker)IBA 12/2023 - 02/2021
4	Monomeric GTP-Binding ProteinsIBA 10/2022 - 04/2018
4	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 04/2018 - 08/2010
4	Neuropilin-2IBA 05/2011 - 11/2004
2	C-Reactive ProteinIBA 12/2023 - 05/2022
2	epithelial membrane protein-1IBA 10/2021 - 10/2018
2	Indicators and Reagents (Reagents)IBA 03/2021 - 10/2019
2	Actins (F Actin)IBA 05/2011 - 01/2008
1	rho GTP-Binding Proteins (rho GTP-Binding Protein)IBA 12/2023
1	LDL CholesterolIBA 01/2023
1	LDL Lipoproteins (beta Lipoproteins)IBA 01/2023
1	Serum AlbuminIBA 05/2022
1	Glycoproteins (Glycoprotein)IBA 01/2020
1	Membrane Proteins (Integral Membrane Proteins)IBA 10/2019
1	NIP 151IBA 01/2019
1	Potassium Channels (Potassium Channel)IBA 01/2019
1	copine IIIIBA 10/2018
1	Growth Differentiation Factor 15IBA 11/2017
1	afadinIBA 11/2017
1	4- (5- benzo(1,3)dioxol- 5- yl- 4- pyridin- 2- yl- 1H- imidazol- 2- yl)benzamideIBA 01/2017
1	Poly I-CIBA 02/2016
1	Immunologic Adjuvants (Immunologic Adjuvant)IBA 02/2016
1	LipopolysaccharidesIBA 02/2016
1	LigandsIBA 01/2016
1	AlbuminsIBA 01/2016
1	Protein Isoforms (Isoforms)IBA 01/2016
1	dipeptidyl peptidase IIIIBA 01/2016
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2016
1	Type 3 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 3)IBA 01/2016
1	Tumor Biomarkers (Tumor Markers)IBA 01/2016
1	Glutathione (Reduced Glutathione)IBA 06/2015
1	Alcohol Dehydrogenase (Alcohol Dehydrogenase (NAD+))IBA 06/2015

Therapy/Procedure

9	Activities of Daily Living (ADL) 02/2024 - 05/2018
7	Length of Stay 12/2023 - 12/2019
7	Therapeutics 10/2023 - 01/2013
2	Palliative Care (Palliative Therapy) 01/2023 - 05/2022
1	Pancreatectomy 02/2024
1	Polypharmacy 01/2024
1	Subacute Care 12/2023
1	Preoperative Exercise 01/2023
1	Radiotherapy 05/2022
1	Dentures 03/2022
1	Foot Orthoses 03/2022
1	Stroke Rehabilitation 12/2021
1	Gastrostomy 12/2021
1	Prostheses and Implants (Prosthesis) 10/2021