Toshiaki Okuno Selected Research

methyl 4- (((3- (6,7- dimethoxy- 2- (methylamino)quinazolin- 4- yl)phenyl)amino)carbonyl)benzoate

12/2015

An inhaled phosphodiesterase 4 inhibitor E6005 suppresses pulmonary inflammation in mice.

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Toshiaki Okuno Research Topics

Disease

13	Inflammation (Inflammations) 01/2023 - 09/2005
4	Sepsis (Septicemia) 01/2022 - 01/2017
3	Wounds and Injuries (Trauma) 03/2023 - 06/2014
3	Lung Injury 01/2022 - 10/2016
3	Atopic Dermatitis (Atopic Eczema) 07/2019 - 01/2019
3	Asthma (Bronchial Asthma) 07/2019 - 08/2013
2	Reperfusion Injury 02/2024 - 12/2021
2	Acute Lung Injury 01/2022 - 10/2016
2	Allergic Conjunctivitis (Giant Papillary Conjunctivitis) 07/2019 - 01/2019
2	Anaphylaxis (Anaphylactic Shock) 07/2019 - 10/2016
2	Colitis 01/2018 - 12/2010
1	Breast Neoplasms (Breast Cancer) 06/2024
1	Neoplasms (Cancer) 06/2024
1	Ischemic Stroke 02/2024
1	Patent Ductus Arteriosus 08/2023
1	Disease Progression 08/2023
1	Glomerulonephritis 01/2023
1	Fibrosis (Cirrhosis) 01/2023
1	Dermatitis 01/2022
1	Nociceptive Pain 01/2022
1	Ischemia 12/2021
1	Renal Insufficiency (Renal Failure) 12/2021
1	Endometriosis 10/2021
1	Primary Hypertrophic Osteoarthropathy (Hypertrophic Osteoarthropathy, Primary) 09/2021
1	Allergic Contact Dermatitis 01/2021
1	Cicatrix (Scar) 11/2020
1	Obesity 10/2020
1	Myocardial Infarction 01/2020
1	Diabetic Retinopathy (Retinopathy, Diabetic) 01/2020
1	Ulcer 01/2020
1	Allergic Rhinitis 07/2019
1	Foodborne Diseases 01/2019
1	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2019
1	Hypersensitivity (Allergy) 01/2019
1	Pruritus (Itching) 01/2019
1	Choroidal Neovascularization 01/2018
1	Insulin Resistance 01/2018
1	Starvation 01/2018
1	Pain (Aches) 10/2017
1	Corneal Ulcer 10/2017
1	Corneal Injuries 10/2017

Drug/Important Bio-Agent (IBA)

8	Leukotriene B4 Receptors (Leukotriene B4 Receptor)IBA 01/2021 - 02/2007
7	Leukotriene B4IBA 01/2023 - 09/2005
7	LipidsIBA 01/2023 - 09/2005
5	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 02/2024 - 10/2004
4	LeukotrienesIBA 07/2019 - 12/2015
3	EicosanoidsIBA 06/2024 - 11/2020
3	Anesthetics (Anesthetic Agents)IBA 06/2024 - 01/2017
3	Isoflurane FDA LinkGeneric 06/2024 - 01/2017
3	Fatty Acids (Saturated Fatty Acids)IBA 12/2021 - 01/2018
2	CytokinesIBA 06/2024 - 12/2015
2	Lymphocyte Function-Associated Antigen-1 (LFA-1)IBA 06/2024 - 01/2017
2	Sevoflurane (Ultane)FDA LinkGeneric 06/2024 - 11/2019
2	Phospholipids (Phosphatides)FDA LinkGeneric 12/2021 - 01/2018
2	EnzymesIBA 01/2021 - 10/2020
2	Omega-3 Fatty Acids (Omega 3 Fatty Acids)IBA 01/2020 - 01/2019
2	Aspirin (Acetylsalicylic Acid)FDA LinkGeneric 07/2019 - 06/2014
2	AcidsIBA 01/2019 - 10/2016
2	12-hydroxy-5,8,10-heptadecatrienoic acidIBA 10/2017 - 06/2014
1	Intravenous AnestheticsIBA 06/2024
1	Bicarbonates (Hydrogen Carbonate)IBA 02/2024
1	ProstaglandinsIBA 08/2023
1	SW033291IBA 03/2023
1	Antigen-Antibody Complex (Immune Complex)IBA 01/2023
1	Antineutrophil Cytoplasmic Antibodies (ANCA)IBA 01/2023
1	Chemotactic FactorsIBA 01/2023
1	IntegrinsIBA 01/2022
1	Liver X ReceptorsIBA 01/2022
1	Formaldehyde (Formol)FDA Link 01/2022
1	Imiquimod (Aldara)FDA LinkGeneric 01/2022
1	Hypnotics and Sedatives (Sedatives)IBA 01/2022
1	Unsaturated Fatty Acids (Polyunsaturated Fatty Acids)IBA 12/2021
1	Soybean Oil FDA LinkGeneric 12/2021
1	CreatinineIBA 12/2021
1	NitrogenIBA 12/2021
1	Urea (Carbamide)FDA LinkGeneric 12/2021
1	salicylhydroxamic acid (SHAM)IBA 12/2021
1	sphingosine 1-phosphate (sphingosine-1-phosphate)IBA 10/2021
1	Cre recombinaseIBA 01/2021
1	Thyroid HormonesIBA 10/2020
1	CatecholaminesIBA 10/2020
1	leukotriene A4 hydrolaseIBA 10/2020
1	Leukotriene A4IBA 10/2020
1	Capsules (Microcapsules)IBA 01/2020
1	Retinaldehyde (Retinal)IBA 01/2020
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 01/2020
1	Eicosapentaenoic AcidIBA 01/2019
1	OxylipinsIBA 01/2019
1	DiglyceridesIBA 01/2018
1	Triglycerides (Triacylglycerol)IBA 01/2018
1	Dextran SulfateIBA 01/2018
1	Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA 10/2017
1	Non-Steroidal Anti-Inflammatory Agents (NSAIDs)IBA 10/2017
1	Ophthalmic Solutions (Eye Drops)IBA 10/2017

Therapy/Procedure

2	Punctures 11/2019 - 01/2017
2	Ligation 11/2019 - 01/2017
1	Investigational Therapies (Experimental Therapy) 02/2024
1	Bone Marrow Transplantation (Transplantation, Bone Marrow) 01/2020
1	General Anesthesia 11/2019
1	Lasers (Laser) 01/2018