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Takashi Nakahara Selected Research

sofosbuvir drug combination ledipasvir

4/2018Efficacy and safety of ledipasvir/sofosbuvir with ribavirin in chronic hepatitis C patients who failed daclatasvir/asunaprevir therapy: pilot study.
11/2017Emergence of drug resistance-associated variants and changes in serum lipid profiles in sofosbuvir plus ledipasvir-treated chronic hepatitis C patients.

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Takashi Nakahara Research Topics

Disease

60Hepatocellular Carcinoma (Hepatoma)
03/2024 - 01/2012
24Fibrosis (Cirrhosis)
03/2024 - 07/2013
21Neoplasms (Cancer)
11/2023 - 08/2012
18Infections
01/2023 - 11/2013
16Liver Cirrhosis (Hepatic Cirrhosis)
03/2024 - 06/2015
16Chronic Hepatitis C
01/2021 - 12/2014
11Non-alcoholic Fatty Liver Disease
01/2023 - 02/2014
8Liver Diseases (Liver Disease)
01/2023 - 02/2014
7Hepatic Encephalopathy
09/2023 - 07/2013
7Chronic Hepatitis B
01/2021 - 01/2016
6Neoplasm Metastasis (Metastasis)
11/2023 - 10/2018
6Inflammation (Inflammations)
01/2023 - 04/2010
5Hepatitis B
01/2023 - 03/2017
5Thrombosis (Thrombus)
04/2021 - 06/2015
5Disease Progression
04/2020 - 04/2011
3Type 2 Diabetes Mellitus (MODY)
01/2023 - 01/2018
3Sarcopenia
02/2020 - 10/2018
3Dyslipidemias (Dyslipidemia)
08/2019 - 11/2012
3Hemorrhage
01/2018 - 11/2015
2Portal Hypertension
03/2024 - 11/2020
2Hypertension (High Blood Pressure)
11/2023 - 08/2019
2Proteinuria
11/2023 - 08/2023
2Acute-On-Chronic Liver Failure
10/2023 - 10/2023
2Acute Liver Failure (Fulminant Hepatic Failure)
09/2023 - 12/2017
2Post-Cardiac Arrest Syndrome
01/2023 - 01/2015
2Insulin Resistance
03/2022 - 02/2014
2Alcoholic Fatty Liver
07/2021 - 11/2012
2Hepatitis
01/2021 - 12/2018
2Wounds and Injuries (Trauma)
01/2021 - 11/2015
2Necrosis
01/2021 - 01/2018
2Microsatellite Instability
10/2020 - 07/2020
2Hepatitis C
09/2020 - 12/2014
2Edema (Dropsy)
02/2020 - 08/2016
2Chronic Hepatitis (Chronic Active Hepatitis)
01/2020 - 12/2018
2Lymphatic Metastasis
08/2019 - 08/2012

Drug/Important Bio-Agent (IBA)

21lenvatinibIBA
11/2023 - 01/2019
13Antiviral Agents (Antivirals)IBA
01/2023 - 08/2016
13InterferonsIBA
11/2020 - 07/2013
12Bevacizumab (Avastin)FDA Link
03/2024 - 08/2021
12atezolizumabIBA
03/2024 - 08/2021
12Sorafenib (BAY 43-9006)FDA Link
01/2021 - 01/2012
11Biomarkers (Surrogate Marker)IBA
03/2024 - 01/2018
8Ribavirin (Virazole)FDA LinkGeneric
01/2020 - 12/2014
6CytokinesIBA
09/2023 - 01/2009
6Proteins (Proteins, Gene)FDA Link
08/2023 - 12/2009
6Glucose (Dextrose)FDA LinkGeneric
01/2023 - 11/2014
6Hemoglobins (Hemoglobin)IBA
01/2023 - 05/2009
6Aspartate Aminotransferases (Aspartate Transaminase)IBA
01/2023 - 12/2017
6AntigensIBA
01/2021 - 11/2016
6asunaprevirIBA
01/2020 - 08/2016
6daclatasvirIBA
01/2020 - 08/2016
5Alanine Transaminase (SGPT)IBA
01/2023 - 03/2014
5Hepatitis B Surface Antigens (HBsAg)FDA Link
01/2021 - 03/2017
5DNA (Deoxyribonucleic Acid)IBA
01/2021 - 05/2014
5SofosbuvirIBA
11/2020 - 06/2017
4alpha-Fetoproteins (alpha-Fetoprotein)IBA
02/2024 - 05/2016
4NucleotidesIBA
01/2023 - 01/2018
4Blood Glucose (Blood Sugar)IBA
01/2023 - 01/2017
4regorafenibIBA
01/2021 - 09/2018
3nasIBA
03/2024 - 06/2020
3Interleukin-6 (Interleukin 6)IBA
10/2023 - 12/2009
3Interleukin-8 (Interleukin 8)IBA
09/2023 - 12/2009
3Prothrombin (Factor II)IBA
09/2023 - 12/2017
3BilirubinIBA
08/2023 - 12/2017
3Cisplatin (Platino)FDA LinkGeneric
06/2022 - 08/2012
3EnzymesIBA
02/2021 - 10/2019
3Tyrosine Kinase InhibitorsIBA
01/2021 - 01/2020
3Immunoglobulins (Immunoglobulin)IBA
01/2021 - 11/2016
3Fetal Proteins (Fetoprotein)IBA
11/2020 - 01/2012
3NucleosidesIBA
01/2019 - 01/2018
3HMGB1 Protein (HMG1)IBA
01/2018 - 12/2009
2Alkaline PhosphataseIBA
03/2024 - 10/2019
2CreatinineIBA
08/2023 - 08/2016
2AlbuminsIBA
08/2023 - 10/2019
2Therapeutic UsesIBA
01/2023 - 07/2021
2LipidsIBA
01/2023 - 11/2017
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
01/2022 - 11/2012
2Carrier Proteins (Binding Protein)IBA
01/2022 - 09/2020
2Immune Checkpoint InhibitorsIBA
02/2021 - 10/2020
2glecaprevir and pibrentasvirIBA
01/2021 - 01/2020
2pembrolizumabIBA
10/2020 - 07/2020
2Adrenal Cortex Hormones (Corticosteroids)IBA
07/2020 - 01/2009
2pibrentasvirIBA
04/2020 - 03/2019
2glecaprevirIBA
04/2020 - 03/2019
2RNA (Ribonucleic Acid)IBA
01/2020 - 04/2018
2AmmoniaIBA
08/2019 - 01/2019
2ChemokinesIBA
07/2019 - 01/2018
2ledipasvirIBA
12/2018 - 11/2017
2entecavirFDA Link
12/2018 - 01/2018

Therapy/Procedure

52Therapeutics
03/2024 - 11/2010
12Drug Therapy (Chemotherapy)
06/2022 - 08/2012
8Radiotherapy
01/2023 - 08/2012
5Liver Transplantation
09/2023 - 03/2017
3Hepatectomy
01/2022 - 08/2012
3Surgical Portasystemic Shunt (Portosystemic Shunt)
08/2019 - 07/2013
3Resuscitation
10/2016 - 01/2015
2Aftercare (After-Treatment)
10/2023 - 01/2023
2Cardiopulmonary Resuscitation (CPR)
01/2023 - 11/2015
2Induced Hypothermia
01/2023 - 01/2015
2Bariatric Surgery
01/2022 - 07/2021