Abstract | BACKGROUND: CASE SUMMARY: A 52-year-old female with a long-standing history of asthma, acral paraesthesia, subcutaneous nodules, and recurrent chest pain treated with anti-inflammatory drugs was admitted to our hospital with chest pain, repolarization disturbances, eosinophilia, and increased troponin levels. After an initial evaluation by coronary angiography, echocardiography and cardiac magnetic resonance, a definitive diagnosis of EM was made with the help of an endomyocardial biopsy. The aetiological diagnosis of EM as a manifestation of tissue involvement in EGPA was concluded after ruling out other possible causes of eosinophilia and with the help of other diagnostic criteria for EGPA ( asthma, eosinophilia, and neuropathy). Therefore, we started with a high dosage of glucocorticoids, and attained relief of symptoms and normalization of eosinophilic count after a few days. DISCUSSION: In cases of myocarditis (particularly if associated with eosinophilia), EM is a manifestation of EGPA and should be considered for a prompt differential diagnosis. Endomyocardial biopsy represents the gold standard for the diagnosis of EM. The mainstay of therapy for EM is immunosuppressive drugs to help prevent its evolution to a fulminant form and chronic progression towards restrictive cardiomyopathy.
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Authors | Ludovica Blumetti, Maria Luisa De Perna, Michael Reinehr, Giovanni Pedrazzini |
Journal | European heart journal. Case reports
(Eur Heart J Case Rep)
Vol. 5
Issue 10
Pg. ytab399
(Oct 2021)
ISSN: 2514-2119 [Electronic] England |
PMID | 34738066
(Publication Type: Case Reports)
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Copyright | © The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology. |