18F-FDG PET/CT and 68Ga-FAPI-4 PET/CT Findings of Bilateral Knee Osteoarthritis in a Patient With Uveal Malignant Melanoma.

Abstract

ABSTRACT:

We present the findings of 68Ga-FAPI-4 PET/CT and 18F-FDG PET/CT of a metastatic malignant melanoma patient with osteoarthritis. A 65-year-old woman with a history of metastatic uveal malignant melanoma was referred to 18F-FDG PET/CT for restaging after enucleation and chemotherapy. 18F-FDG PET/CT imaging showed high radiotracer uptake in liver metastases; additionally mild uptake due to osteoarthritis was observed in both knees. However, although 68Ga-FAPI-4 showed lower uptake in liver lesions, it showed a more prominent uptake in both knee joints compared with 18F-FDG.

• Authors: Özge Erol Fenercioğlu, Ediz Beyhan, Nurhan Ergül, Esra Arslan, Tevfik Fikret Çermik
• Journal: Clinical nuclear medicine (Clin Nucl Med) Vol. 47 Issue 2 Pg. e144-e146 (Feb 01 2022) ISSN: 1536-0229 [Electronic] United States
• PMID: 34319962 (Publication Type: Case Reports, Journal Article)
• Copyright: Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Chemical References

• 68Ga-FAPI
• Quinolines
• Fluorodeoxyglucose F18

Topics

• Aged
• Female
• Fluorodeoxyglucose F18
• Humans
• Melanoma
• Osteoarthritis, Knee
• Positron Emission Tomography Computed Tomography
• Quinolines