Lung disorders induced by respirable organic chemicals.

Abstract

Respirable organic chemicals were originally thought to cause allergic respiratory diseases, such as bronchial asthma and hypersensitivity pneumonitis, and believed not to cause lung disorders derived from inflammatory or fibrotic processes such as pulmonary fibrosis and interstitial pneumonitis. It has recently been reported, however, that exposure to organic chemicals can cause interstitial lung diseases. In this review, we discuss the clinical features of occupational asthma and hypersensitivity pneumonitis, as well as other lung disorders, including interstitial pneumonitis, caused by humidifier disinfectants in Korea and by a cross-linked acrylic acid-based polymer (CL-PAA) in Japan.

• Authors: Yasuo Morimoto, Chinatsu Nishida, Taisuke Tomonaga, Hiroto Izumi, Kazuhiro Yatera, Kazuo Sakurai, Yangho Kim
• Journal: Journal of occupational health (J Occup Health) Vol. 63 Issue 1 Pg. e12240 (Jan 2021) ISSN: 1348-9585 [Electronic] Australia
• PMID: 34128301 (Publication Type: Journal Article, Review)
• Copyright: © 2021 The Authors. Journal of Occupational Health published by John Wiley & Sons Australia, Ltd on behalf of The Japan Society for Occupational Health.

Chemical References

• Acrylic Resins
• Disinfectants
• Organic Chemicals
• carbopol 940

Topics

• Acrylic Resins (toxicity)
• Adult
• Alveolitis, Extrinsic Allergic (chemically induced)
• Asthma, Occupational (chemically induced)
• Disinfectants (toxicity)
• Female
• Humans
• Humidifiers
• Inhalation Exposure (adverse effects)
• Japan
• Lung Diseases (chemically induced)
• Lung Diseases, Interstitial (chemically induced)
• Male
• Middle Aged
• Occupational Diseases (chemically induced)
• Occupational Exposure (adverse effects)
• Organic Chemicals (toxicity)
• Republic of Korea