Interstitial Lung Diseases (Interstitial Lung Disease)

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2858 relevant articles (130 outcomes, 206 trials/studies) found for this Disease

Description: A heterogeneous group of noninfectious, nonmalignant disorders of the lower respiratory tract, affecting primarily the alveolar wall structures but also often involving the small airways and blood vessels of the lung parenchyma. "Interstitial" refers to the fact that the interstitium of the alveolar walls is thickened, usually by fibrosis. This group of diseases is usually inflammatory. (Dorland, 27th ed; Wyngarden, Cecil Textbook of Medicine, 19th ed, p396)

Also Known As:

Interstitial Lung Disease; Interstitial Pneumonia; Interstitial Pneumonitis; Lung Diseases, Interstitial; Disease, Interstitial Lung; Diseases, Interstitial Lung; Interstitial Pneumonias; Interstitial Pneumonitides; Lung Disease, Interstitial; Pneumonias, Interstitial; Pneumonitides, Interstitial; Pneumonia, Interstitial; Pneumonitis, Interstitial

Relationship Network

Disease Context: Research Results

Respiratory Tract Diseases: 372

Lung Diseases: 8779

Interstitial Lung Diseases: 2858

Pulmonary Fibrosis: 3591

Wegener Granulomatosis: 1598

Pneumoconiosis: 1316

Bronchiolitis Obliterans: 766

Extrinsic Allergic Alveolitis: 705

Langerhans-Cell Histiocytosis: 633

Pulmonary Sarcoidosis: 539

Anti-Glomerular Basement Membrane Disease: 496

Radiation Pneumonitis: 288

Related Diseases

1.	Infection
2.	Systemic Scleroderma (Systemic Sclerosis)
3.	Pulmonary Fibrosis (Hamman Rich Syndrome)
4.	Dermatomyositis (Dermatopolymyositis)
5.	Myositis (Idiopathic Inflammatory Myopathies)
413 Diseases and 1624 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Experts

1.	Fujita, Jiro: 8 articles (12/2007 - 10/2002)
2.	Yoshinouchi, Takeo: 8 articles (12/2007 - 01/2002)
3.	Ohtsuki, Yuji: 8 articles (12/2007 - 10/2002)
4.	Chida, Kingo: 7 articles (05/2008 - 07/2003)
5.	Colby, Thomas V: 7 articles (01/2008 - 01/2003)
6.	Kinnula, Vuokko L: 7 articles (09/2007 - 01/2002)
7.	Martinez, Fernando J: 6 articles (01/2008 - 01/2003)
8.	Yamadori, Ichiro: 6 articles (01/2007 - 10/2002)
9.	Suda, Takafumi: 5 articles (05/2008 - 07/2003)
10.	Mukae, Hiroshi: 5 articles (01/2008 - 05/2004)

Drugs and Biologics

Drugs and Important Biological Agents (IBA) related to Interstitial Lung Diseases:

1.	Cyclosporine (Ciclosporin)FDA LinkGeneric 01/01/2006 - "Treatment with high-dose corticosteroid and cyclosporin A steadily improved his interstitial pneumonia" 04/01/2001 - "Successful therapy of cyclosporin A in a case with idiopathic interstitial pneumonia]" 08/01/1991 - "Cyclosporin A may be effective in the treatment of interstitial lung disease of unknown aetiology" 06/01/2005 - "Our case suggested that combination therapy with steroid, Cyclosporin-A, and IVCY is useful for the treatment of progressive interstitial pneumonia with DM." 04/01/2001 - "It suggests that cyclosporin A may be useful for the treatment of idiopathic interstitial pneumonia." Get all the results and reference details, order at left...
2.	Cyclophosphamide (Cytoxan)FDA Link 06/01/2005 - "Additional intravenous Cyclophosphamide (IVCY) was initiated on the 6th hospital day, and interstitial pneumonia was markedly improved" 11/01/2003 - "Cyclophosphamide may soon be proven effective against interstitial lung disease." 12/01/2006 - "Cyclophosphamide (CYC) seems to be beneficial in interstitial lung disease associated with SSc" 10/01/2001 - "A case of idiopathic interstitial pneumonia that responded well to intermittent intravenous administration of high doses of cyclophosphamide and a steroid]" 01/01/1996 - "Four months later, he developed severe interstitial pneumonitis, and his symptoms were not improved by high-dose steroid pulse and cyclophosphamide pulse treatment" Get all the results and reference details, order at left...
3.	Prednisolone (Predate)FDA LinkGeneric 10/01/2003 - "In the first patient, oral prednisolone (PSL) treatment (20 mg day) improved the interstitial pneumonia, but PSL has now been tapered to 17.5 mg day" 05/01/1997 - "Oral prednisolone treatment was started and the retinopathy was improved, but was complicated by acute interstitial pneumonia" 06/01/1989 - "An experimental study on prednisolone-induced interstitial pneumonia caused by Pneumocystis carinii]" 02/01/2008 - "A 64-year-old woman had been treated with prednisolone (PSL) for interstitial pneumonia (IP) of unknown origin since 1988" 03/01/2006 - "From February 7, 40mg /day prednisolone was started because of aggravation of interstitial pneumonia" Get all the results and reference details, order at left...
4.	Methylprednisolone FDA LinkGeneric 09/01/1995 - "However, this induced severe interstitial pneumonitis, which was not cured by discontinuation of the drug, but disappeared completely with six episodes of methylprednisolone pulse therapy" 06/01/2000 - "In 1988, interstitial pneumonia (IP) was pointed out and she was treated with methylprednisolone (mPSL) pulse therapy" 12/01/1999 - "Increasing dose of methylprednisolone pulse therapy treats desquamative interstitial pneumonia in a child." 11/01/1998 - "Chronic interstitial lung disease in children: response to high-dose intravenous methylprednisolone pulses." 10/01/1997 - "Although his illness was not diagnosed, he was treated with a high dose of methylprednisolone (1 g/day for 3 days) for acute interstitial lung disease" Get all the results and reference details, order at left...
5.	Adrenal Cortex Hormones (Corticosteroids)IBA 03/01/1997 - "Corticosteroids and immunosuppressive drugs have been used to treat lymphocytic interstitial pneumonia, and they were effective in this case." 10/19/2002 - "Although early observations showed some benefit of corticosteroids, it is now well established that these studies in fact included a proportion of other corticosteroid-sensitive diseases, such as non-specific interstitial pneumonia" 01/01/2006 - "The patient was following up as a diagnosis of usual interstitial pneumonia and treating with corticosteroids and azothiopurine" 03/01/2005 - "Administration of corticosteroids with steroid pulse therapy resulted in with improvement of interstitial pneumonia" 11/23/2002 - "It may also be a cryptogenic interstitial pneumonia with characteristic clinical and imaging features and especially an excellent response to corticosteroids." Get all the results and reference details, order at left...
6.	Methotrexate (Mexate)FDA LinkGeneric 06/01/2006 - "Interstitial pneumonitis is a well documented, rare complication of methotrexate (MTX)" 03/01/2002 - "CONCLUSION: There is no evidence to suggest clinically, from HRCT assessment or serial pulmonary function tests, that low-dose methotrexate is associated with chronic interstitial lung disease." 03/01/2002 - "Two fatal cases of methotrexate-induced interstitial pneumonitis]" 05/01/1994 - "Low-dose methotrexate is proving to be a problem because granulomatous interstitial pneumonitis develops in 5% of those patients receiving it" 07/01/1992 - "The only complication associated with methotrexate therapy was one patient in whom cytomegalovirus interstitial pneumonitis developed while on therapy" Get all the results and reference details, order at left...
7.	Ganciclovir (Cytovene)FDA LinkGeneric 06/01/1992 - "IVIgG appears to be effective in the prevention or amelioration of CMV-related pathology if given frequently and has also dramatically improved the survival of patients with established interstitial pneumonia when used in combination with ganciclovir" 07/01/1991 - "Preliminary results of controlled trials of prophylactic ganciclovir show reduced CMV-related interstitial pneumonia" 04/01/2000 - "WBC was 4.5 x 10(9)/L on day 18, and descended for a time during treating interstitial pneumonia with Ganciclovir" 04/01/1998 - "The most common form of IP in patients given prophylactic ganciclovir is now idiopathic interstitial pneumonitis." 04/01/1993 - "She was receiving immunosuppressive therapy with CYA and a corticosteroid for acute GVHD, and maintenance therapy with ganciclovir for interstitial pneumonia (IP) caused by CMV, but was not neutropenic" Get all the results and reference details, order at left...
8.	SteroidsIBA 01/01/1989 - "In seven patients there was symptomatic improvement with steroid therapy, but three patients who were not treated with steroids died as a result of interstitial pneumonia" 06/01/1988 - "One patient with chronic infiltrates showed a lymphocytic interstitial pneumonia, which responded well to steroids" 11/01/2002 - "This study was performed to find the rationale for administering steroids to patients with idiopathic interstitial pneumonia (IIP), which was unlikely to be usual interstitial pneumonia (UIP) but was not surgically biopsied" 01/01/2008 - "She was diagnosed with interstitial pneumonia and treated with steroids" 12/01/2006 - "Therapy for idiopathic interstitial pneumonias: steroids--and what else?]" Get all the results and reference details, order at left...
9.	Azathioprine (Imuran)FDA LinkGeneric 01/01/1996 - "Azathioprine was very effective against the interstitial pneumonia in this case, but general conclusions about the most effective type of immunosuppressive agent and the timing of its administration must await the results of further study." 02/12/2006 - "Azathioprine-associated interstitial pneumonitis" 02/12/2006 - "Azathioprine-associated interstitial pneumonitis]" 08/01/1984 - "Azathioprine-associated interstitial pneumonitis." 02/01/1978 - "Azathioprine should be considered in the differential diagnosis of interstitial pneumonitis in all patients taking the drug." Get all the results and reference details, order at left...
10.	ADM protocolIBA 02/01/2008 - "Her aDM was complicated with skin ulceration due to vasculopathy, but complicated interstitial pneumonia was not severe" 01/01/2008 - "ADM is sometimes accompanied by interstitial pneumonia that shows a rapid progressive course associated with a poor prognosis" 12/01/2007 - "Positive anti-Jo-1 was seen in 2 of 96 patients (2%; one CDM and one ADM, both with interstitial lung disease), reflecting an overall low prevalence of this autoantibody, or a potential problem with the laboratory assay" 03/01/2007 - "Our data suggest that ADM-associated interstitial pneumonia takes an aggressive course even when the radiological and histological features are consistent with NSIP" 09/01/2004 - "Therefore, we should appropriately treat interstitial pneumonia in ADM even if it is NSIP." Get all the results and reference details, order at left...
804 Drugs and Important Bio-Agents and 2433 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

Therapies and Procedures

1.	Transplantation (Transplant Recipients) 09/18/1982 - "Six patients are alive and well in complete clinical, cytogenetic, and haematological remission, 1-3 years after transplantation, despite complications in three patients (one had interstitial pneumonitis, one had mild veno-occlusive disease of the liver, and one had severe GvHD)." 06/01/1991 - "Variables significantly associated with both increased survival and relapse-free survival included transplantation in first remission, younger patient age, and not developing interstitial pneumonia" 04/01/1982 - "Passive immunization with a CMV immune plasma has been found to be effective for the prevention of interstitial pneumonia after marrow transplantation" 04/01/2000 - "RESULTS: After transplantation, the patient had grade II acute GVHD and cytomegalovirus(CMV) interstitial pneumonia; he was cured" 01/01/2005 - "This study suggests that HHV-7 may play an important role in causing interstitial pneumonia in patients who are not transplant recipients." Get all the results and reference details, order at left...
2.	Transplants (Transplant) 07/01/1988 - "Six patients died in complete remission from cytomegalovirus (CMV) interstitial pneumonitis and three remain alive in complete remission 2, 3 and 13 months after transplant" 02/01/1994 - "Common odds ratios for the trials reporting cytomegalovirus interstitial pneumonia, cytomegalovirus death, overall death and graft loss ranged from 0.47 to 0.69" 05/01/1993 - "AIMS--To study the association between cytomegalovirus (CMV) excretion and interstitial pneumonitis in allogeneic bone marrow transplant (BMT) recipients, with reference to donor and recipient CMV antibody response" 11/01/1992 - "STUDY OBJECTIVE: To determine the value of pulmonary function tests (PFTs) in predicting the development of human cytomegalovirus (CMV)-associated interstitial pneumonia (IP) in allogeneic bone marrow transplant (BMT) recipients" 10/01/2007 - "A 16-year-old Japanese boy who had been suffering from interstitial lung disease received bilateral lung transplant from a braindead donor in the United States" Get all the results and reference details, order at left...
3.	Bone Marrow Transplantation (Transplantation, Bone Marrow) 06/01/1979 - "New attempts are being made to improve the results : (1) better cytoreductive therapy preceding transplanation, (2) bone marrow transplantation during remission of the disease, (3) prevention of interstitial pneumonitis by modifications of the TBI technique." 01/01/2006 - "This study evaluated patients for the influence of the dose rate and lung dose of fractionated total body irradiation (TBI) in preparation for allogeneic bone marrow transplantation (BMT) on the subsequent development of interstitial pneumonitis (IP)" 04/01/2004 - "The aim of this study is to evaluate the incidence of interstitial pneumonitis following fractionated total body irradiation conditioning for bone marrow transplantation with varying lung doses due to shielding technique and different dose-rates" 12/01/1986 - "Interstitial pneumonitis in allogeneic bone marrow transplantation: a report from the Japanese BMT Study Group." 06/01/1985 - "In an attempt to reduce the incidence of lethal cytomegalovirus (CMV) interstitial pneumonitis after allogenic bone marrow transplantation 49 patients were randomized in a multicenter controlled study to receive either CMV-hyperimmune globulin or a control immune globulin with low anticytomegalovirus titer" Get all the results and reference details, order at left...
4.	Aftercare (After-Treatment) 01/01/1997 - "We suggest that corticosteroid pulse treatment is effective in acute exacerbatins of idiopathic interstitial pneumonia and that effectiveness should be evaluated three months after treatment." 10/01/2003 - "During the average post-treatment follow-up period of 31.0 days (range 3 to 76 days), the opacities quickly improved after treatment in 6 patients; however, in 2 patients with pre-existing interstitial pneumonitis the opacities were refractory" 09/01/2007 - "The scheduled number of cycles could be completed in all but one patient who developed interstitial pneumonia 2 days after treatment" 03/01/2006 - "Thirteen cases with nonspecific interstitial pneumonia (NSIP) were evaluated before and after treatment" 10/01/2004 - "Resolution of lymphocytic interstitial pneumonitis in an HIV infected adult after treatment with HAART." Get all the results and reference details, order at left...
5.	Lung Transplantation 12/01/1999 - "The physical status of the patient with idiopathic interstitial pneumonia was markedly improved after pulmonary rehabilitation, and she did not need to undergo lung transplantation" 12/01/2004 - "Lung transplantation remains the only therapeutic option shown to improve survival for many end-stage interstitial lung diseases" 09/01/2005 - "The aim of the study was to identify prognostic factors that would differentiate patients with interstitial lung disease between those with and without a chance to survive until lung transplantation" 07/01/2006 - "BACKGROUND: Patients with interstitial lung disease (ILD) very frequently die before the opportunity to receive lung transplantation (LTx)" 09/01/2005 - "It appears that simple functional tests of the cardiorespiratory system may define survival of patients with interstitial lung disease waiting for lung transplantation." Get all the results and reference details, order at left...
69 Therapies and Procedures and 617 more articles analyzed in the Full Patient-Physician Summary Report, order at left...

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