Characteristics of Pulmonary Auscultation in Patients with 2019 Novel Coronavirus in China.

Abstract

BACKGROUND:

Effective auscultations are often hard to implement in isolation wards. To date, little is known about the characteristics of pulmonary auscultation in novel coronavirus (COVID-19) pneumonia.

OBJECTIVES:

The aim of this study was to explore the features and clinical significance of pulmonary auscultation in COVID-19 pneumonia using an electronic stethoscope in isolation wards.

METHODS:

This cross-sectional, observational study was conducted among patients with laboratory-confirmed COVID-19 at Wuhan Red-Cross Hospital during the period from January 27, 2020, to February 12, 2020. Standard auscultation with an electronic stethoscope was performed and electronic recordings of breath sounds were analyzed.

RESULTS:

Fifty-seven patients with average age of 60.6 years were enrolled. The most common symptoms were cough (73.7%) during auscultation. Most cases had bilateral lesions (96.4%) such as multiple ground-glass opacities (69.1%) and fibrous stripes (21.8%). High-quality auscultation recordings (98.8%) were obtained, and coarse breath sounds, wheezes, coarse crackles, fine crackles, and Velcro crackles were identified. Most cases had normal breath sounds in upper lungs, but the proportions of abnormal breath sounds increased in the basal fields where Velcro crackles were more commonly identified at the posterior chest. The presence of fine and coarse crackles detected 33/39 patients with ground-glass opacities (sensitivity 84.6% and specificity 12.5%) and 8/9 patients with consolidation (sensitivity 88.9% and specificity 15.2%), while the presence of Velcro crackles identified 16/39 patients with ground-glass opacities (sensitivity 41% and specificity 81.3%).

CONCLUSIONS:

The abnormal breath sounds in COVID-19 pneumonia had some consistent distributive characteristics and to some extent correlated with the radiologic features. Such evidence suggests that electronic auscultation is useful to aid diagnosis and timely management of the disease. Further studies are indicated to validate the accuracy and potential clinical benefit of auscultation in detecting pulmonary abnormalities in COVID-19 infection.

• Authors: Bo Wang, Yanbin Liu, Ye Wang, Wanhong Yin, Tao Liu, Dan Liu, Diandian Li, Mei Feng, Yanlin Zhang, Zong'an Liang, Ziqiao Fu, Siyun Fu, Weimin Li, Nian Xiong, Gang Wang, Fengming Luo
• Journal: Respiration; international review of thoracic diseases (Respiration) Vol. 99 Issue 9 Pg. 755-763 ( 2020) ISSN: 1423-0356 [Electronic] Switzerland
• PMID: 33147584 (Publication Type: Journal Article, Observational Study, Research Support, Non-U.S. Gov't)
• Copyright: © 2020 S. Karger AG, Basel.

Chemical References

• Anti-Bacterial Agents
• Antiviral Agents
• Glucocorticoids

Topics

• Adult
• Aged
• Aged, 80 and over
• Anti-Bacterial Agents (therapeutic use)
• Antiviral Agents (therapeutic use)
• Auscultation
• COVID-19 (diagnosis, diagnostic imaging, physiopathology, therapy)
• China
• Cough (physiopathology)
• Cross-Sectional Studies
• Electrical Equipment and Supplies
• Female
• Glucocorticoids (therapeutic use)
• Humans
• Lung (diagnostic imaging, physiopathology)
• Male
• Middle Aged
• Oxygen Inhalation Therapy
• Respiration, Artificial
• Respiratory Sounds (physiopathology)
• SARS-CoV-2
• Sensitivity and Specificity
• Severity of Illness Index
• Smartphone
• Sound Spectrography
• Sputum
• Stethoscopes
• Tomography, X-Ray Computed
• Young Adult
• COVID-19 Drug Treatment