(1) Background: The prevalence of allergic
respiratory diseases is still rising and efforts towards holistic treatments should be made. Although
speleotherapy is widely applied in Europe to treat chronic airway diseases, the existing scientific evidence is rather low. Recreational winter exercise has been shown to improve allergic airway
inflammation, but little is known about the combined effects of
speleotherapy and recreational winter exercise. (2) Methods: In this clinical study we investigated the effects of winter exercise and
speleotherapy on adults with
allergic rhinitis and/or
asthma. The
speleotherapy group (n = 23) participated in a ten-day combined winter exercise and
speleotherapy program and the exercise group (n = 18) joined a full-day winter sports program. The effects on allergic airway
inflammation, quality of life, spirometry and cardiorespiratory fitness were assessed. (3) Results: No significant effects were found for fractional exhaled
nitric oxide or nasal
nitric oxide. Quality of life (p < 0.001 time effect) and allergic symptoms (p < 0.001 time effect) were improved in the
speleotherapy and in the exercise group. (4) Conclusions: Winter exercise alone and winter exercise in combination with
speleotherapy improve quality of life and allergic symptoms in adults with
allergic rhinitis and/or
asthma. Further studies are required to investigate the specific effects of
speleotherapy. To our knowledge, this is the first investigation examining
speleotherapy in combination with winter exercise. Recreational outdoor winter exercise and
speleotherapy may be recommended for highly functioning patients with good disease control.