Characteristics of in peripheral blood of 70 hospitalized patients and 8 diarrhea patients with COVID-19.

Abstract

Objective: To analyze the blood test indicators of patients after infection of COVID-19 in Chongqing and analyze the clinical indicators of 8 patients with diarrhea. Materials and Methods: From January 26, 2019 to February 13, 2020, 70 patients diagnosed with 2019-nCoV according to the World Health Organization interim guidance for NCP and divided into diarrhea and non-diarrhea groups. The laboratory tests liver and kidney function, blood routine, coagulation function, and immune status. Results: The study population included 70 hospitalized patients with confirmed CONV-2019. NCP patients (43males and 27 females) with a mean age of 48.57±17.80 (9~82) years and only 4.3% of patients have lung-related diseases. The positive rate of ESR, CRP, PT, IL6, lymphocyte count, GGT, Prealbumin and CD4 was more than 50%. We further analyzed the differences between 8 diarrhea patients and 62 non-diarrhea patients. Among these indicators, only Lymphocyte, CRP, Prealbumin and Cystatin C positive rate is more than 50%. Although there is no statistical difference in GGT, 100% of the 7 patients tested decreased. Conclusion: Our data recommended that the ESR, CRP, PT, IL6, lymphocyte count, GGT, prealbumin and CD4 have important value in the diagnosis of COVID-19, and the decrease of GGT may be an important indicator for judging the intestinal dysfunction of patients.

• Authors: Xiao-Yu Wei, Ding Jing, Bei Jia, Qing Li, Xia-Qia Zhou, Ming-Feng Gong, Jing-Bo Zou, Qiang Zhang, Wen-Xiang Huang, Wen-Guang Tian
• Journal: International journal of medical sciences (Int J Med Sci) Vol. 17 Issue 9 Pg. 1142-1146 ( 2020) ISSN: 1449-1907 [Electronic] Australia
• PMID: 32547309 (Publication Type: Journal Article)
• Copyright: © The author(s).

Chemical References

• Biomarkers
• gamma-Glutamyltransferase

Topics

• Adolescent
• Adult
• Age Factors
• Aged
• Aged, 80 and over
• Betacoronavirus (isolation & purification)
• Biomarkers (blood)
• COVID-19
• Child
• Coronavirus Infections (blood, complications, diagnosis, virology)
• Diarrhea (blood, diagnosis, virology)
• Female
• Humans
• Male
• Middle Aged
• Pandemics
• Pneumonia, Viral (blood, complications, diagnosis, virology)
• SARS-CoV-2
• Young Adult
• gamma-Glutamyltransferase (blood)