Usefulness of Cardiac Magnetic Resonance in the Diagnosis of Löffler Endocarditis Secondary to Eosinophilic Granulomatosis with Polyangiitis.

Abstract

A 40-year-old man who was diagnosed with bronchial asthma and eosinophilia was transferred to our hospital due to a worsening respiratory status. He was diagnosed with eosinophilic granulomatosis with polyangiitis (EGPA), and eosinophilic pneumoniae. Cardiac magnetic resonance (CMR) imaging indicated Löffler endocarditis. Treatment was initiated using intravenous methylprednisolone, cyclophosphamide, and heparin as anticoagulation therapy. Three months later, CMR showed the improvement of the LV myocardium. In this case, the early diagnosis of Löffler endocarditis by CMR could prevent systemic embolism and CMR was useful for assessing the curative effects of steroid and immunosuppressant therapy.

• Authors: Kana Kurokawa, Eiryu Sai, Eri Hayashi, Kentaro Minowa, Koji Sugano, Takuma Yoshihara, Tadashi Miyazaki, Makoto Hiki, Takayuki Yokoyama, Masaru Suzuki, Katsumi Miyauchi
• Journal: Internal medicine (Tokyo, Japan) (Intern Med) Vol. 58 Issue 2 Pg. 239-242 (Jan 15 2019) ISSN: 1349-7235 [Electronic] Japan
• PMID: 30146590 (Publication Type: Case Reports, Journal Article)

Chemical References

• Anti-Inflammatory Agents
• Anticoagulants
• Cyclophosphamide
• Heparin
• Methylprednisolone

Topics

• Adult
• Anti-Inflammatory Agents (therapeutic use)
• Anticoagulants (therapeutic use)
• Asthma (complications)
• Cyclophosphamide (therapeutic use)
• Endocarditis (diagnostic imaging, etiology)
• Eosinophilia (complications)
• Granulomatosis with Polyangiitis (complications, drug therapy)
• Heart (diagnostic imaging)
• Heparin (therapeutic use)
• Humans
• Magnetic Resonance Imaging
• Male
• Methylprednisolone (therapeutic use)