Abstract | BACKGROUND: METHODS: The study consisted of 7,762 subjects divided into four groups-nonobese/nondiabetic, obese/nondiabetic, nonobese/diabetic and obese/diabetic-based on the BMI classification and their FBG. Anthropometric characteristics were measured and blood was collected for the evaluation of fasted lipid profile, FBG and serum hs-CRP levels. RESULTS: Several clinical and biochemical characteristics were significantly different among the four groups: FBG, P < 0.001; total cholesterol (TC), P < 0.001; and triglyceride (TG), P < 0.001. The subjects with a serum hs-CRP >3 mg/dl had higher TC (P < 0.001), low-density lipoprotein cholesterol ( LDL-C, P < 0.001), TG (P < 0.001), fat percentage (P < 0.001), and systolic and diastolic blood pressure (P < 0.001) compared with subjects with a serum hs-CRP <3 mg/dl. Multivariate analysis showed FBG, LDL-C, and waist circumference (WC) associated with increased serum hs-CRP levels (P < 0.001). CONCLUSIONS: FBG, LDL-C, WC and gender are independently associated with serum hs-CRP concentrations.
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Authors | Mahmoud Ebrahimi, Ali Reza Heidari-Bakavoli, Sara Shoeibi, Seyed Reza Mirhafez, Mohsen Moohebati, Habibollah Esmaily, Hamed Ghazavi, Maryam Saberi Karimian, Seyed Mohammad Reza Parizadeh, Maryam Mohammadi, Hossein Mohaddes Ardabili, Gordon A Ferns, Majid Ghayour-Mobarhan |
Journal | Journal of clinical laboratory analysis
(J Clin Lab Anal)
Vol. 30
Issue 5
Pg. 672-6
(Sep 2016)
ISSN: 1098-2825 [Electronic] United States |
PMID | 26857805
(Publication Type: Journal Article)
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Copyright | © 2016 Wiley Periodicals, Inc. |
Chemical References |
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Topics |
- C-Reactive Protein
(metabolism)
- Cardiovascular Diseases
(blood, complications)
- Diabetes Mellitus
(blood)
- Female
- Humans
- Linear Models
- Male
- Middle Aged
- Obesity
(blood, complications)
- Risk Factors
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