Abstract | OBJECTIVE: The effects of C-peptide on adipose tissue, an organ involved in the development of obesity and insulin resistance, are not yet well known. The aim of this study was to determine whether C-peptide could be involved in the regulation of the adipocytokine synthesis in human visceral adipose tissue. METHODS: RESULTS: CONCLUSIONS:
C-peptide may be involved in the regulation of leptin and visfatin secretion, molecules intimately involved in energy homeostasis processes, through PI3K or PKB pathways.
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Authors | Sara Garcia-Serrano, Carolina Gutiérrez-Repiso, Montserrat Gonzalo, Juan Garcia-Arnes, Sergio Valdes, Federico Soriguer, Vidal Perez-Valero, Miguel A Alaminos-Castillo, Juan Francisco Cobos-Bravo, Francisco J Moreno-Ruiz, Alberto Rodriguez-Cañete, Francisca Rodríguez-Pacheco, Eva Garcia-Escobar, Eduardo García-Fuentes |
Journal | Obesity (Silver Spring, Md.)
(Obesity (Silver Spring))
Vol. 23
Issue 8
Pg. 1607-15
(Aug 2015)
ISSN: 1930-739X [Electronic] United States |
PMID | 26146822
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Copyright | © 2015 The Obesity Society. |
Chemical References |
- Adipokines
- C-Peptide
- Leptin
- Nicotinamide Phosphoribosyltransferase
- Phosphatidylinositol 3-Kinases
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Topics |
- Adipokines
(chemistry)
- Adipose Tissue
(drug effects)
- Adult
- C-Peptide
(blood, chemistry)
- Female
- Glucose Tolerance Test
(methods)
- Humans
- Leptin
(blood, chemistry)
- Male
- Nicotinamide Phosphoribosyltransferase
(blood, chemistry)
- Phosphatidylinositol 3-Kinases
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